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Pranoprofen

Pranoprofen Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99% Package:1KG;7USD
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99% Package:5KG;1KG Remarks:C15H13NO3

Lastest Price from Pranoprofen manufacturers

  • Pranoprofen
  • US $0.00 / KG
  • 2020-12-01
  • CAS:52549-17-4
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • Pranoprofen
  • US $1.00-1.00 / KG
  • 2020-05-12
  • CAS:52549-17-4
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
  • Pranoprofen
  • US $1.00-1.00 / KG
  • 2020-05-12
  • CAS:52549-17-4
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 50tons
Pranoprofen Basic information
Product Name:Pranoprofen
Synonyms:PRANOPROFEN;(RS)-Pranoprofen;5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, a-methyl- (9CI);a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid;dl-Pranoprofen;Niflan;Y 8004;pyranoprofen
CAS:52549-17-4
MF:C15H13NO3
MW:255.27
EINECS:682-035-7
Product Categories:NIFLAN;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;>97%,BR
Mol File:52549-17-4.mol
Pranoprofen Structure
Pranoprofen Chemical Properties
Melting point 182-183°
Boiling point 398.5°C (rough estimate)
density 1.1654 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
pka4.27±0.10(Predicted)
form powder
color white to beige
CAS DataBase Reference52549-17-4(CAS DataBase Reference)
Safety Information
RIDADR UN 2811 6.1 / PGIII
RTECS DJ3100950
ToxicityLD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
MSDS Information
Pranoprofen Usage And Synthesis
Chemical PropertiesOff-White Solid
OriginatorNiflan, Yoshitomi ,Japan ,1981
UsesPranoprofen is an anti-inflammatory used in ophthalmology.
Manufacturing ProcessA mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic FunctionAnalgesic, Antiinflammatory
Pranoprofen Preparation Products And Raw materials
Raw materialsHydrochloric acid
Tag:Pranoprofen(52549-17-4) Related Product Information
3-Phenylpropionic acid Ibuprofen l-Pranoprofen,(S)-(+)-Pranoprofen (R)-Pranoprofen,(R)-(-)-Pranoprofen,d-Pranoprofen ALFA-METHYL-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER 2-(4-METHOXY-3-METHYLPHENYL)ACETALDEHYDE N,N-dimethylcarbamoylmethyl alpha,2-dimethyl-5H-1-benzopyrano(2,3-b)pyridine-7-acetate ALFA-METHYL-ALFA-CYANO-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER 4-METHOXY-3-METHYLPHENYLACETIC ACID Pranoprofen Ascoric Acid Centchroman Imidocarb dipropionate Folic acid Propionic acid Nandrolone phenylpropionate 3-(4-Hydroxyphenyl)propionic acid Ethyl 2-(Chlorosulfonyl)acetate