- N-Isopropylbenzylamine
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- $20.00 / 1kg
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2025-02-18
- CAS:102-97-6
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 10000
- N-Isopropylbenzylamine
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- $10.00 / 1ASSAYS
-
2025-02-18
- CAS:102-97-6
- Min. Order: 1ASSAYS
- Purity: 99%
- Supply Ability: 100kg
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| N-Isopropylbenzylamine Basic information |
Product Name: | N-Isopropylbenzylamine | Synonyms: | N-ISOPROPYLBENZYLAMINE;N-BENZYL-N-ISOPROPYLAMINE;N-(b-Hydroxyethyl)pyrrolidine;N-Isopropylbenzenemethanamine;N-Isopropylphenylmethanamine;N-Isopropylbenzylamine,97%;N-ISOPROPYLBENZYLAMINE / N-BENZYLISOPROPYLAMINE;N-(1-Methylethyl)-be | CAS: | 102-97-6 | MF: | C10H15N | MW: | 149.23 | EINECS: | 203-067-6 | Product Categories: | API;102-97-6;1 | Mol File: | 102-97-6.mol |  |
| N-Isopropylbenzylamine Chemical Properties |
Hazard Codes | Xi | Risk Statements | 36/37/38 | Safety Statements | 26-36 | RIDADR | 2735 | WGK Germany | 3 | TSCA | Yes | HazardClass | 8 | PackingGroup | III | HS Code | 29214980 |
| N-Isopropylbenzylamine Usage And Synthesis |
Chemical Properties | CLEAR VERY SLIGHTLY YELLOW TO YELLOW LIQUID | Uses | N-Isopropylbenzylamine, can be used as an intermediate in the synthesis of pharmaceutical compounds,and as a precursor to the manufacture of some drugs. Due to it’s similarity in appearance and physical properties to methamphetamine, it has been recently come under consideration of DEA. | Application | N-Isopropylbenzylamine was used as ligand in the preparation and characterization of bis(cyclopentadienyl)magnesium. It was also used in the synthesis of N-benzylideneisopropylamine-N-oxide. | Preparation | N-benzylisopropylamine is synthesized by the reduction reaction of N-isopropylbenzamide or prepared from benzylamine and acetone by reductive amination reaction. | General Description | N-isopropylbenzylamine is a structural isomer of methamphetamine, is one of the most common adulterants. It forms amine adducts with magnesocene at ambient temperature in toluene. | Cytotoxicity | The toxicity of N-isopropylbenzylamine was evaluated in SH-SY5Y, PC12, and SN4741 cell lines. Cells were treated with 0.3–10 mM N-isopropylbenzylamine for 24 hours, and cell viability was measured using MTT assay. N-isopropylbenzylamine concentration-dependently reduced cell viability in these cells. The IC50 values of N-isopropylbenzylamine on cell viability were 3.47, 1.49, and 3.21 mM for SH-SY5Y cells, PC12 cells, and SN4741 cells, respectively. N-isopropylbenzylamine produced toxicity in cell lines that model neurons. Moreover, the activation of nNOS and the production of intracellular NO might be involved in N-isopropylbenzylamine-induced toxicity in SN4741 cells[1]. | References | [1] Peng Xu . “N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro.” Toxicology 480 (2022): Article 153337. |
| N-Isopropylbenzylamine Preparation Products And Raw materials |
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