| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-Human IgG1 (Fc specific) antibody produced in mouse
Purity:clone HP-6001, ascites fluid Package:.5ML Remarks:I9388-.5ML
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:clone HP-6001, ascites fluid
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| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-HUMAN IGG1 FC Basic information |
| | ANTI-HUMAN IGG1 FC Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-HUMAN IGG1 FC Usage And Synthesis |
| Uses | Monoclonal Anti-Human IgG1 (Fc specific) antibody is suitable for use in ELISA and immunoblot. | | General Description | Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Monoclonal Anti-Human IgG1 (Fc specific) antibody is specific for an epitope in the Fc region of human IgG1 and does not detect IgG2, IgG3, and IgG4. The association constant of this antibody with its ligand is estimated to be 1x(107) L/M. This product clone has been tested for specificity using various immunoassays in the IUIS/WHO study. | | Biochem/physiol Actions | IgG1 has a molecular weight of 146 kDa and is an abundantly expressed IgG subclass. IgG1 deficiencies contribute to overall decrease in total IgG levels resulting in hypogammaglobulinemia. IgG1 promotes bacterial phagocytosis and mediates vaccine-induced protection from infection. The ratio of IgG2a to IgG1 is crucial for immune response against Leishmania tropica infection. It has high binding affinity towards the Fcγ receptors (FcγR). |
| | ANTI-HUMAN IGG1 FC Preparation Products And Raw materials |
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