n-Butyryl tri-n-hexyl citrate manufacturers
- n-Butyryl tri-n-hexyl citrate
-
- $50.00 / 1KG
-
2023-12-23
- CAS:82469-79-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
|
| | n-Butyryl tri-n-hexyl citrate Basic information |
| Product Name: | n-Butyryl tri-n-hexyl citrate | | Synonyms: | 2,3-propanetricarboxylicacid,2-(1-oxobutoxy)-trihexylester;trihexylo-butyrylcitrate;n-Butyryl tri-n-hexyl citrate;BUTYRYL TRIHEXYL CITRATE;BTHC;TRIHEXYL O-BUTYRYLCITRATE 99%;Butyryl tri-n-hexyl citrate;Trihexyl 2-(butyryloxy)-1,2,3-propanetricarboxylate | | CAS: | 82469-79-2 | | MF: | C28H50O8 | | MW: | 514.69 | | EINECS: | 413-890-4 | | Product Categories: | | | Mol File: | 82469-79-2.mol |  |
| | n-Butyryl tri-n-hexyl citrate Chemical Properties |
| | n-Butyryl tri-n-hexyl citrate Usage And Synthesis |
| Uses | Trihexyl O-Butyrylcitrate is a non-toxic plasticizer, widely used in non-toxic PVC granulation, medical products, soft children's toys, ink coatings, etc. | | Application | Trihexyl O-Butyrylcitrate can be used as an intermediate in pharmaceutical synthesis. | | Synthesis | Trihexyl O-Butyrylcitrate was prepared as follows: 1) To a 1 liter four-neck flask equipped with a stirrer, immersion thermometer, subsurface nitrogen sparge tube and Barrett trap with condenser 330 g n-hexanol, 180 g citric acid and 50 ml heptane. The reaction mass was heated to reflux (about 120°C) with a heating mantle and 1.5 grams of tetra-n-butyl titanate esterification catalyst was added. The reaction mass was esterified at 120-140°C until the acidity was less than 2 mgKOH/g acidity. The pressure was reduced to 20 mmHg using a vacuum pump to distill off excess n-hexanol and heptane azeotrope. The ester-containing reaction mass was then stripped with fresh steam at a temperature of 130-140° C. and full vacuum until no residual n-hexanol was detected by gas chromatography.
2) The ester-containing reaction mass was cooled to 90°C, and 0.4 g of concentrated sulfuric acid was added dropwise with stirring. n-Butyric anhydride (166 g) was added dropwise with stirring, maintaining the acylation temperature between 90-110°C. The acylation reaction mixture was stirred and allowed to proceed for 2 hours to prepare the acylated ester. response quality. By-product butyric acid was removed by vacuum distillation at 110°C. |
| | n-Butyryl tri-n-hexyl citrate Preparation Products And Raw materials |
|