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Isatoic Anhydride

Isatoic Anhydride Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-571-85586718
Email: sales@capotchem.com
Products Intro: Product Name:Isatoic anhydride
CAS:118-48-9
Purity:97%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:4H-3,1-Benzoxazine-2,4(1H)-dione
CAS:118-48-9
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:118-48-9
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:1H-benzo[d][1,3]oxazine-2,4-dione
CAS:118-48-9
Purity:98% Package:25G;50G;100G;500G;1KG;10KG;50KG
Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-025-86736275
Email: dana.jiang@royal-chem.com
Products Intro: Product Name:Isatoic anhydride
CAS:118-48-9
Purity:99.00% Package:25kg/bag;400kg/bag

Lastest Price from Isatoic Anhydride manufacturers

  • Isatoic Anhydride
  • US $2.00 / kg
  • 2019-07-06
  • CAS:118-48-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: ask
Isatoic Anhydride Basic information
Product Name:Isatoic Anhydride
Synonyms:Isatoic;Isatoic acid anhydride;isatoicacidanhydride;Isatonicanhydride;Isatosαureanhydrid;n-carboxy-anthranilicacicyclicanhydride;N-Carboxyanthranilicanbydride;n-carboxyanthranilicanhydride
CAS:118-48-9
MF:C8H5NO3
MW:163.13
EINECS:204-255-0
Product Categories:Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;pharmacetical
Mol File:118-48-9.mol
Isatoic Anhydride Structure
Isatoic Anhydride Chemical Properties
Melting point 233 °C (dec.)(lit.)
Boiling point 290.19°C (rough estimate)
density 1,52 g/cm3
vapor density 5.6 (vs air)
refractive index 1.5510 (estimate)
Fp 308 °C
storage temp. Store below +30°C.
solubility 0.3g/l
pka11.06±0.20(Predicted)
form Powder
color Beige to brown
Water Solubility decomposes
Sensitive Moisture Sensitive
BRN 136786
CAS DataBase Reference118-48-9(CAS DataBase Reference)
NIST Chemistry ReferenceIsatoic anhydride(118-48-9)
EPA Substance Registry System2H-3,1-Benzoxazine-2,4(1H)-dione (118-48-9)
Safety Information
Hazard Codes Xi
Risk Statements 36-43
Safety Statements 24-26-37
WGK Germany 1
RTECS DM3100000
3
Autoignition Temperature>600 °C
TSCA Yes
HS Code 29349990
Hazardous Substances Data118-48-9(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: > 6400 mg/kg LD50 dermal Rabbit > 2000 mg/kg
MSDS Information
ProviderLanguage
4H-3,1-Benzoxazine-2,4(1H)-dione English
SigmaAldrich English
ACROS English
ALFA English
Isatoic Anhydride Usage And Synthesis
Chemical PropertiesBEIGE TO BROWN POWDER
UsesIsatoic anhydride is a potent inactivator of α-chymotrypsin and inactivates stoichiometrically. Isatoic Anhydride is an important compound in the preparation of serine protease inhibitors.
DefinitionA bicyclic molecule composed of a benzene ring attached at the oand mpositions to a heterocyclic ring. It forms useful anthranilic acid derivatives by reaction with hydrogen.
Purification MethodsRecrystallise it from EtOH or 95% EtOH (30mL/g) or dioxane (10mL/g) and dry it in a vacuum. [Wagner & Fegley Org Synth Coll Vol III 488 1955, Ben-Ishai & Katchalski J Am Chem Soc 74 3688 1952, UV: Zentmyer & Wagner J Org Chem 14 967 1949, Beilstein 27 II 299, 27III/IV 3330.]
Isatoic Anhydride Preparation Products And Raw materials
Raw materialsAnthranilic acid
Tag:Isatoic Anhydride(118-48-9) Related Product Information
1-(Piperazin-1-Ylcarbonyl)-2H-3,1-Benzoxazine-2,4(1H)-Dione 6-CHLORO-2H-1,4-BENZOXAZINE-2,3(4H)-DIONE 3-OXIME 2H-1,4-benzoxazine-2,3(4H)-dione 5-FLUORO-2H-3,1-BENZOXAZINE-2,4(1H)-DIONE 5-AMINOISATOIC ANHYDRIDE 5-NITROISATOIC ANHYDRIDE AKOS BBS-00002894 6-Hydroxy-2H-3,1-benzoxazine-2,4(1H)-dione 4-CARBOXYLIC-ISATOIC ANHYDRIDE 6,8-dichloro-2H-3,1-benzoxazine-2,4(1H)-dione N-ALLYLISATOIC ANHYDRIDE 6-CHLOROISATIN 5-CHLORO-1-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE 6-METHYL ISATINIC ANHYDRIDE 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione,1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione,2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- 4-NITRO-ISATOIC ANHYDRIDE 1-Benzyl-2H-3,1-benzoxazine-2,4(1H)-dione Isatoic Anhydride