|
| 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Basic information |
Product Name: | 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole | Synonyms: | 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole;1H-BenziMidazole, 6-broMo-4-fluoro-2-Methyl-1-(1-Methylethyl)-;6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole;6-bromo-4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazole;6-Bromo-4-fluoro-1-isopropyl-2-methylbenzimidazole;Abemaciclib Impurity 1;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole ISO 9001:2015 REACH;Abemaciclib Impurity 1 D12 | CAS: | 1231930-33-8 | MF: | C11H12BrFN2 | MW: | 271.13 | EINECS: | 807-019-0 | Product Categories: | API | Mol File: | 1231930-33-8.mol | |
| 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Chemical Properties |
Boiling point | 353.4±22.0 °C(Predicted) | density | 1.49 | storage temp. | Sealed in dry,Room Temperature | pka | 3.48±0.10(Predicted) | InChI | InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3 | InChIKey | SJQZRZLUEGCXFN-UHFFFAOYSA-N | SMILES | C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1 |
| 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Usage And Synthesis |
Uses | 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy. | Flammability and Explosibility | Not classified |
| 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole Preparation Products And Raw materials |
|