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GSK-2126458

GSK-2126458 Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-571-85586718 +86(0)13336195806
Email: sales@capotchem.com
Products Intro: Product Name:GSK2126458
CAS:1086062-66-9
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:GSK2126458
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: career henan chemical co
Tel: +86-0371-55982848
Email: sales@coreychem.com
Products Intro: Product Name:GSK-2126458
CAS:1086062-66-9
Purity:99% Package:1kg;2USD
Company Name: Biochempartner
Tel: 0086-13720134139
Email: candy@biochempartner.com
Products Intro: Product Name:GSK2126458
CAS:1086062-66-9
Purity:98% HPLC LCMS Package:10G;20G
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:GSK-2126458
CAS:1086062-66-9
Purity:0.99 Package:5KG;1KG

GSK-2126458 manufacturers

  • GSK-2126458
  • $2.00 / kg
  • 2019-07-06
  • CAS:1086062-66-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
GSK-2126458 Basic information
Product Name:GSK-2126458
Synonyms:GSK2126458;GSK-2126458;GSK2126458; GSK-2126458;2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide;GSK2126458 (HYR-582);CS-55;Omipalisib GSK2126458;HYR-582
CAS:1086062-66-9
MF:C25H17F2N5O3S
MW:505.5
EINECS:629-873-1
Product Categories:Akt;mTOR;Aromatics;PI3K/Akt/mTOR;Inhibitors;PI3K;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:1086062-66-9.mol
GSK-2126458 Structure
GSK-2126458 Chemical Properties
Melting point 187-189℃
Boiling point 715.6±70.0 °C(Predicted)
density 1.45
pka6.23±0.40(Predicted)
Safety Information
HS Code 29350090
MSDS Information
GSK-2126458 Usage And Synthesis
DescriptionGSK2126458 is a potent inhibitor of phosphoinositide 3-kinase isoforms (Kis = 19, 130, 24, and 60 pM for p110α, β, δ, and γ, respectively). It also inhibits mTOR in both mTORC1 and mTORC2 (Kis = 180 and 300 nM, respectively), as well as several common mutant forms of p110α. GSK2126458 is orally bioavailable, displays favorable pharmacokinetics, and shows efficacy in tumor growth models. GSK2126458 positively combines with inhibitors of discoidin domain receptor 1 (DDR1) inhibitor DDR1-IN-1 (Item No. 18092) to suppress the growth of SNU-1040 colorectal cancer cells.
UsesA highly potent inhibitor of PI3K and the mammalian target of Rapamycin.
GSK-2126458 Preparation Products And Raw materials
Tag:GSK-2126458(1086062-66-9) Related Product Information
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