- 6-O-Benzylguanine
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- $150.00 / 1kg
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2024-04-22
- CAS:19916-73-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5ton
- O6-Benzylguanine
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- $0.00 / 1g
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2024-03-16
- CAS:19916-73-5
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 20 tons
- O6-Benzylguanine
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- $122.00 / 1KG
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2024-01-11
- CAS:19916-73-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | 6-O-Benzylguanine Basic information |
| | 6-O-Benzylguanine Chemical Properties |
| Melting point | 193(dec.) | | Boiling point | 459.3±55.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | storage temp. | room temp | | solubility | methanol: 20 mg/mL | | form | solid | | pka | 7.47±0.20(Predicted) | | color | Off-White to Light Yellow | | CAS DataBase Reference | 19916-73-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29339900 |
| | 6-O-Benzylguanine Usage And Synthesis |
| Chemical Properties | Light Yellow Solid | | Uses | O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Uses | An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents. | | Biochem/physiol Actions | O6-Benzylguanine (O6BG) inhibits methylguanine methyltransferase (MGMT) by blocking the active site through benzyl group transfer. The use of O6BG with bis-chloroethylnitrosourea (BCNU) or carmustine is effective in treating solid tumors including lymphomas, melanomas and sarcoma. |
| | 6-O-Benzylguanine Preparation Products And Raw materials |
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