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| | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Basic information |
| Product Name: | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester | | Synonyms: | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester;BIBF1120 Intermediate4;Nintedanib ethanesulfonate intermediates;(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl este;methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)-;Nintedanib Intermediate 4;(3E)-2 | | CAS: | 1168150-46-6 | | MF: | C18H15NO4 | | MW: | 309.32 | | EINECS: | 927-895-9 | | Product Categories: | | | Mol File: | 1168150-46-6.mol |  |
| | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Chemical Properties |
| Boiling point | 523.8±50.0 °C(Predicted) | | density | 1.273±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 10.62±0.20(Predicted) | | form | Solid | | color | Light Yellow |
| | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Usage And Synthesis |
| Uses | (E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity. |
| | (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Preparation Products And Raw materials |
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