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Rubitecan

Rubitecan Suppliers list
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Rubitecan
CAS:91421-42-0
Purity:HPLC>=98% Package:5mg
Company Name: Chengdu Greenpure Biopharma CO.,Ltd
Tel: 18283602253
Email: jancyzheng@gcgreenpure.com
Products Intro: Product Name:Rubitecan
CAS:91421-42-0
Purity:98% Package:20mg;100mg;1g Remarks:Alkaloids
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Rubitecan
CAS:91421-42-0
Purity:99% Package:1KG;7USD
Company Name: Chengdu GLP Biotech Co., Ltd
Tel: 13350802083
Email: scglp@glp-china.com
Products Intro: Product Name:Rubitecan
CAS:91421-42-0
Purity:98% Package:1g;5g;10g
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: 18080483897
Email: maggie@biopurify.com
Products Intro: Product Name:Rubitecan
CAS:91421-42-0
Purity:90%~98% HPLC Package:20mg;100mg;500mg;1g Remarks:BP1229

Lastest Price from Rubitecan manufacturers

  • Rubitecan
  • US $0.00-0.00 / 公斤
  • 2020-05-03
  • CAS:91421-42-0
  • Min. Order: 1公斤
  • Purity: 99.0%
  • Supply Ability: 800 ton
  • Rubitecan
  • US $7.00 / KG
  • 2019-07-06
  • CAS:91421-42-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
Rubitecan Basic information
Description Reference
Product Name:Rubitecan
Synonyms:RFS 2000;9-Nitrocellulose camptothecine;9-NITRO-CPT;9-NITRO-20(S)-CAMPTOTHECIN;(4s)-4-ethyl-4-hydroxy-10-nitro-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;RUBETICAN;RUBITECAN;orathecin
CAS:91421-42-0
MF:C20H15N3O6
MW:393.35
EINECS:
Product Categories:Anti-cancer & immunity;API;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:91421-42-0.mol
Rubitecan Structure
Rubitecan Chemical Properties
Melting point 182-186°C
alpha D23 +27° (c = 0.2 in CH3OH-CHCl3, 1:4)
Boiling point 816.3±65.0 °C(Predicted)
density 1.63
Fp 106℃
storage temp. Room temp
pka11.16±0.20(Predicted)
Merck 14,8288
CAS DataBase Reference91421-42-0(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS UQ0493300
HS Code 29399990
MSDS Information
Rubitecan Usage And Synthesis
DescriptionRubitecan, marketed by Supergen as Orathecin, is a promising oral treatment for solid melanoma, prostate, breast, ovarian, and other cancers, as well as leukemia. It is a derivative of camptothecin, a topoisomerase inhibitor known from Chinese Traditional Medicine. It selectively targets the critical S-stage of cellular reproduction – particularly in acidic environments, as in many cancer cells – relaxing DNA supercoiling and generating lethal breaks in the DNA. Due to insolubility, its biological delivery mechanism is not yet effective, and it has not been approved for clinical use.
Referencehttps://www.sciencedirect.com/topics/medicine-and-dentistry/rubitecan
https://en.wikipedia.org/wiki/Rubitecan
https://en.wikipedia.org/wiki/Topoisomerase_inhibitor
https://en.wikipedia.org/wiki/Camptothecin#cite_note-Y.Pommier_2003-14
https://www.ncbi.nlm.nih.gov/pubmed/1995300
Chemical PropertiesYellow Amorphous Powder
UsesSemisynthetic camptothecin which inhibits DNA topoisomerase I. Prodrug of 9-aminocamptothecin. Antineoplastic
DefinitionChEBI: A pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin.
Rubitecan Preparation Products And Raw materials
Tag:Rubitecan(91421-42-0) Related Product Information
10-Nitrocamptothecin 12-nitrocamptothecin 10-HYDROXY-9-NITROCAMPTOTHECIN Rubitecan NITROGEN DIOXIDE (+)-Camptothecin