| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:GSK-J1 (lithium salt)
Purity:>98% Package:3500RMB/1mg
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| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:GSK-J1 (lithium salt)
Purity:>98% Package:1240RMB/10mg
|
| Company Name: |
SPIRO PHARMA
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| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:GSK-J1 (lithiuM salt)
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| Company Name: |
Absin Bioscience Inc.
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| Tel: |
021-38015121 18438616290 |
| Email: |
lanwu@univ-bio.com |
| Products Intro: |
Product Name:GSK-J1 lithium salt
Package:10mg;50mg Remarks: 见爱必信官网
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| Company Name: |
Chunchuang (Wuhan) Technology Co., Ltd
|
| Tel: |
15727060112 |
| Email: |
yutianchun2007@126.com |
| Products Intro: |
Product Name:GSK-J1 (lithiuM salt)
CAS:2309668-29-7
Purity:97%~99% HPLC Package:1mg;1g;10g;100g;1Kg;10Kg;100Kg;1T
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| | GSK-J1 (lithiuM salt) Basic information |
| | GSK-J1 (lithiuM salt) Chemical Properties |
| form | Solid | | color | White to off-white |
| | GSK-J1 (lithiuM salt) Usage And Synthesis |
| Uses | GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B. | | IC 50 | KDM6 | | References | [1] Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8. DOI:10.1038/nature11262
[2] Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2 DOI:10.1038/nature13688
[3] Horton JR, et al. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases. J Biol Chem. 2016 Feb 5;291(6):2631-46. DOI:10.1074/jbc.M115.698449 |
| | GSK-J1 (lithiuM salt) Preparation Products And Raw materials |
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