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| | LDN-214117 Basic information |
| Product Name: | LDN-214117 | | Synonyms: | LDN-214117;1-(4-(6-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenyl)piperazine;1-[4-[6-Methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]piperazine;LDN-214117;LDN214117;CS-1539;Piperazine, 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]-;LDN-214117 USP/EP/BP;LDN214117,LDN-214117,ALK2,BMP4,BMP2,Transforming growth factor beta receptors,LDN 214117,BMP6,TGF-β Receptor,diffuse intrinsic pontine glioma(DIPG),oral,ALK3,fibrodysplasia ossificans progressiva (FOP),ALK5,type I receptor kinases,ALK1,bone morphogenetic proteins (BMPs) | | CAS: | 1627503-67-6 | | MF: | C25H29N3O3 | | MW: | 419.52 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1627503-67-6.mol |  |
| | LDN-214117 Chemical Properties |
| Boiling point | 567.9±50.0 °C(Predicted) | | density | 1.134±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF:30.0(Max Conc. mg/mL);71.51(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.19(Max Conc. mM)
DMSO:42.67(Max Conc. mg/mL);101.7(Max Conc. mM)
Ethanol:54.0(Max Conc. mg/mL);128.72(Max Conc. mM) | | pka | 8.86±0.10(Predicted) | | form | Powder |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 |
| | LDN-214117 Usage And Synthesis |
| Uses | LDN 214117 is a highly selective ALK2 inhibitor. |
| | LDN-214117 Preparation Products And Raw materials |
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