- Fmoc-Val-Cit-PAB-PNP
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- $0.00 / 5g
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2024-03-29
- CAS:863971-53-3
- Min. Order: 5g
- Purity: >95.00%
- Supply Ability: 5g
- FMoc-Val-Cit-PAB-PNP
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- $7.00 / 1KG
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2020-02-19
- CAS: 863971-53-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
- FMoc-Val-Cit-PAB-PNP
-
- $7.00 / 1KG
-
2020-02-19
- CAS: 863971-53-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | FMoc-Val-Cit-PAB-PNP Basic information |
| Product Name: | FMoc-Val-Cit-PAB-PNP | | Synonyms: | FMoc-Val-Cit-PAB-PNP;{4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]pentanamido]phenyl}methyl 4-nitrophenyl carbonate;Moc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PAB-PNP, >95%;L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE);4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate;(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate | | CAS: | 863971-53-3 | | MF: | C40H42N6O10 | | MW: | 766.8 | | EINECS: | | | Product Categories: | Pharmaceutical;ADCs;ADC-Linker;ADC-Linkers | | Mol File: | 863971-53-3.mol |  |
| | FMoc-Val-Cit-PAB-PNP Chemical Properties |
| Melting point | 189 °C(dec.) | | Boiling point | 1024.0±65.0 °C(Predicted) | | density | 1.335±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | form | powder to crystal | | pka | 10.63±0.46(Predicted) | | color | White to Light yellow | | Sequence | Fmoc-Val-Cit-PAB-PNP |
| | FMoc-Val-Cit-PAB-PNP Usage And Synthesis |
| Description | Fmoc-Val-Cit-PAB-PNP is a a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. PNP group is a good leaving group when reacting with amine bearing payload. | | Biological Activity | Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs). |
| | FMoc-Val-Cit-PAB-PNP Preparation Products And Raw materials |
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