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| | K201 hemifumarate Basic information |
| Product Name: | K201 hemifumarate | | Synonyms: | 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone hemifumarate;JTV-519 hemifumarate;K201 hemifumarate;1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone;4-[3-(4-Benzylpiperidin-1-yl)propionyl]-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine;3-(4-benzylpiperidin-1-yl)-1-(7-methoxy-2,3-dihydrobenzo[f][1,4]thiazepin-4(5H)-yl)propan-1-one(K201 hemifumarate);JTV-519
(K201;JTV-519 free base | | CAS: | 145903-06-6 | | MF: | C25H32N2O2S | | MW: | 424.6 | | EINECS: | | | Product Categories: | | | Mol File: | 145903-06-6.mol |  |
| | K201 hemifumarate Chemical Properties |
| Boiling point | 615.1±55.0 °C(Predicted) | | density | 1.153±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | pka | 8.93±0.10(Predicted) | | color | white to beige | | BRN | 10598851 |
| Hazard Codes | N,Xn | | Risk Statements | 50/53-53-22 | | Safety Statements | 60-61 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 |
| | K201 hemifumarate Usage And Synthesis |
| Biochem/physiol Actions | JTV-519 is a potent inhibitor or the ryanodine receptor 2 (RYR2) blocker. RYR2 is a cardiac calcium channel that regulates calcium levels in the sarcoplasmic reticulum. JTV-519 stabilizes RYR2 in the closed state. |
| | K201 hemifumarate Preparation Products And Raw materials |
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