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| | (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Basic information |
| | (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Chemical Properties |
| Melting point | 68-70 °C (lit.) | | Boiling point | 124-125 °C/13 mmHg (lit.) | | density | 1.136 | | refractive index | 1.4641 (estimate) | | Fp | 112℃ | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | Powder | | pka | 3.87±0.16(Predicted) | | color | White | | optical activity | [α]20/D +19°, c = 1 in chloroform | | BRN | 1721140 | | CAS DataBase Reference | 17407-55-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 3-10 | | Hazard Note | Irritant | | HS Code | 29181990 |
| | (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Usage And Synthesis |
| Chemical Properties | white fine crystalline powder | | Uses | A useful chiral building block for peptide synthesis. Used in the preparation of the cytotoxic didemnin cyclopeptides and of the antineoplastic agent dolastatin 15. | | Definition | ChEBI: (S)-2-hydroxy-3-methylbutyric acid is the S-enantiomer of 2-hydroxy-3-methylbutyric acid. It is used as a chiral building block for peptide synthesis. It has a role as a chiral reagent and a human metabolite. It is a conjugate acid of a (S)-2-hydroxy-3-methylbutyrate. It is an enantiomer of a (R)-2-hydroxy-3-methylbutyric acid. |
| | (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Preparation Products And Raw materials |
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