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| | 5-Chloroisatoic anhydride Basic information |
| Product Name: | 5-Chloroisatoic anhydride | | Synonyms: | TIMTEC-BB SBB003570;AKOS BBS-00002892;5-CHLOROISATOIC ANHYDRIDE;5-CHLOROISATONIC ANHYDRIDE;6-CHLORO-1,2-DIHYDRO-4 H-3,1-BENZOXAZINE-2,4-DIONE;6-chloro-4h-3,1-benzoxazine-2,4(1h)-dione;5-Chloroisotoic anhydride;6-Chloro-2H-3,1-benzoxazine-2,4(1H)-dione | | CAS: | 4743-17-3 | | MF: | C8H4ClNO3 | | MW: | 197.58 | | EINECS: | 225-255-7 | | Product Categories: | Benzoxazines;Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts | | Mol File: | 4743-17-3.mol |  |
| | 5-Chloroisatoic anhydride Chemical Properties |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 2934999090 |
| | 5-Chloroisatoic anhydride Usage And Synthesis |
| Chemical Properties | White powder | | Uses | 5-Chloroisatoic Anhydride was used as a reagent in the synthesis of 2-acetamidobenzamides bearing the 2-phenoxy functionality which display antiproliferative activity against certain tumor cell lines. Also used in the preparation of inhibitors of delta-5 desaturase. | | Preparation | 5-Chloroisatoic anhydride is prepared from 5-chloro indole (9c) by stirring in a 4:1 mixture of DMF/H2O for 16 h at room temperature.
1 H NMR (DMSO-d6): δ 11.85 (s, br., 1H), 7.96 (dd, J = 0.8, 8.7 Hz, 1H), 7.87 (dd, J = 2.3, 8.7 Hz, 1H), 7.09 (dd, J = 8.8, 0.8 Hz, 1H).
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| | 5-Chloroisatoic anhydride Preparation Products And Raw materials |
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