- BMS-986020
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- $6.68 / 1KG
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2020-01-13
- CAS: 1257213-50-5
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg-1000kg
- BMS-986020
-
- $6.68 / 1KG
-
2020-01-13
- CAS: 1257213-50-5
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg-1000kg
|
| | BMS-986020 Basic information |
| Product Name: | BMS-986020 | | Synonyms: | BMS-986020;CS-2492;(R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid;BMS-986020;BMS 986020;BMS986020;1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid;AM152;Cyclopropanecarboxylic acid, 1-[4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl][1,1'-biphenyl]-4-yl]-;inhibit,idiopathic,AM-152,LPL Receptor,Lysophospholipid Receptor,AM 152,IPF,BMS-986020,fibrosis,pulmonary,BMS 986020,autoradiography,Inhibitor,ARG | | CAS: | 1257213-50-5 | | MF: | C29H26N2O5 | | MW: | 482.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1257213-50-5.mol |  |
| | BMS-986020 Chemical Properties |
| Melting point | 174-180°C | | Boiling point | 664.8±55.0 °C(Predicted) | | density | 1.309±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) | | form | Solid | | pka | 4.19±0.20(Predicted) | | color | White to Off-White |
| | BMS-986020 Usage And Synthesis |
| Description | BMS 986020 is a potent G protein-coupled lysophosphatidic acid receptor 1 (LPA1) antagonist with an IC50 value less than 300 nM for human LPA1 expressing CHO cells. Formulations containing BMS 986020 are being investigated in clinical trials for efficacy in idiopathic pulmonary fibrosis. | | Uses | BMS-?986020 is an LPA-1 antagonist which may be used in the inhibition and treatment of bleomycin-induced pulminary fibrosis. |
| | BMS-986020 Preparation Products And Raw materials |
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