N-Acetyl-Calicheamicin

N-Acetyl-Calicheamicin Suppliers list

Company Name:	BOC Sciences
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Products Intro:	Product Name:N-Acetyl-Calicheamicin CAS:108212-76-6 Purity:95% Package:1 mg Remarks:Reach out to us for more information about custom solutions.

Company Name:	TargetMol Chemicals Inc.
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Company Name:	HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Company Name:	Shenzhen Shengda Pharma Limited
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Company Name:	InvivoChem
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Products Intro:	Product Name:N-Acetyl-Calicheamicin CAS:108212-76-6 Purity:98% Package:2mg Remarks:V33969

N-Acetyl-Calicheamicin manufacturers

N-Acetyl-Calicheamicin Basic information

Product Name:	N-Acetyl-Calicheamicin
Synonyms:	N-Acetyl-Calicheamicin;N-acetylcalicheamicin γ1;N-acetyl-calicheamidn y1;N-Acetyl-Calicheamicin g1;Carbamic acid, [(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyranosyl]oxy]amino]-β-D-glucopyranosyl]oxy]-1-hydr...;N-Acetyl-Calicheamicin γ\|\|\|N-Acetyl-γ-calicheamicin;N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ)
CAS:	108212-76-6
MF:	C57H76IN3O22S4
MW:	1410.38
EINECS:
Product Categories:
Mol File:	108212-76-6.mol

N-Acetyl-Calicheamicin Chemical Properties

density	1.56±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
form	Solid
pka	7.13±0.60(Predicted)
color	White to off-white
InChIKey	WPDOZYZAJKUVRZ-VEKKAAIHNA-N

Safety Information

MSDS Information

N-Acetyl-Calicheamicin Usage And Synthesis

Description	N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic.
Uses	N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ), an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC[1].
References	[1] K C Nicolaou, et al. Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107042118. DOI:10.1073/pnas.2107042118 [2] Breanna S Vollmar, et al. Calicheamicin Antibody-Drug Conjugates with Improved Properties. Mol Cancer Ther. 2021 Jun;20(6):1112-1120. DOI:10.1158/1535-7163.MCT-20-0035

N-Acetyl-Calicheamicin Preparation Products And Raw materials

Raw materials

Tag:N-Acetyl-Calicheamicin(108212-76-6) Related Product Information

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