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| | SPACE peptide Basic information |
| Product Name: | SPACE peptide | | Synonyms: | SPACE peptide;SPACE peptide,AC-TGSTQHQ-CG,Disulfide Bridge 2–10;Glycine, L-alanyl-L-cysteinyl-L-threonylglycyl-L-seryl-L-threonyl-L-glutaminyl-L-histidyl-L-glutaminyl-L-cysteinyl-, cyclic (2→10)-disulfide | | CAS: | 1621717-95-0 | | MF: | C40H63N15O17S2 | | MW: | 1090.15 | | EINECS: | | | Product Categories: | | | Mol File: | 1621717-95-0.mol |  |
| | SPACE peptide Chemical Properties |
| Boiling point | 1870.9±65.0 °C(Predicted) | | density | 1.54±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 3.57±0.10(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Ala-Cys-Thr-Gly-Ser-Thr-Gln-His-Gln-Cys-Gly (Disulfide bridge: Cys2-Cys10) |
| | SPACE peptide Usage And Synthesis |
| Uses | SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid[1][2][3]. | | References | [1] Chen M, et al. Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers. J Control Release. 2014 Jan 10;173:67-74. DOI:10.1016/j.jconrel.2013.10.007
[2] Hsu T, et al. Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15816-21. DOI:10.1073/pnas.1016152108
[3] Kumar S, et al. Peptides as skin penetration enhancers: mechanisms of action. J Control Release. 2015 Feb 10;199:168-78. DOI:10.1016/j.jconrel.2014.12.006 |
| | SPACE peptide Preparation Products And Raw materials |
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