| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Tryptophan Hydroxylase
Purity:affinity isolated antibody, buffered aqueous glycerol soluti Package:1vial Remarks:T8575
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Monoclonal Anti-Tryptophan Hydroxylase antibody produced in mouse
Purity:clone WH-3, ascites fluid Remarks:affinity isolated antibody, buffered aqueous glycerol solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
Vision BioSystems
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| Tel: |
800 753 7264 |
| Email: |
sales.usa@vision-bio.com |
| Products Intro: |
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| Company Name: |
American Qualex
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| Tel: |
949 492 8298 |
| Email: |
info@americanqualex.com |
| Products Intro: |
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| | ANTI-TRYPTOPHAN HYDROXYLASE Basic information |
| | ANTI-TRYPTOPHAN HYDROXYLASE Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| | ANTI-TRYPTOPHAN HYDROXYLASE Usage And Synthesis |
| Uses | Anti-Tryptophan Hydroxylase antibody produced in sheep has been used in:
- immunocytochemistry
- immunohistochemistry
- immunofluorescence
- immunoperoxidase staining
| | General Description | The tryptophan hydroxylase 1 (TPH1) gene spanning 29kbp with 11 exons is mapped to human chromosome 11p15.3-p14. TPH1, is a 444 amino acid protein expressed in the gut, spleen, thymus and also in the pineal gland and the pituitary. | | Biochem/physiol Actions | The tryptophan hydroxylase 1 gene (TPH1) catalyzes the synthesis of 5-hydroxytryptophan, which is a precursor to the neurotransmitter serotonin. Variation in the gene expression affects prefrontal cortex activation during response inhibition. Mutation in the TPH1 gene leads to schizophrenia, irritable bowel syndrome (IBS) in women, suicidal behavior and depressive disorders. The encoded protein plays a vital role in regulation of cardiovascular function. |
| | ANTI-TRYPTOPHAN HYDROXYLASE Preparation Products And Raw materials |
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