| Company Name: |
U-Chemo Scientific(Shanghai) Co.,Ltd
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| Tel: |
021-58380326 13585932672 |
| Email: |
3251669772@qq.com |
| Products Intro: |
Product Name:Sobrerol
CAS:498-71-5
Purity:97%/98% Package:10G/100G/1KG/>10KG Remarks:PA343
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| Company Name: |
TCI (Shanghai) Chemical Trading Co., Ltd.
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| Tel: |
021-61109150 |
| Email: |
sales@tcisct.com |
| Products Intro: |
Product Name:5-(2-hydroxypropan-2-yl)-2-methylcyclohex-2-en-1-ol
CAS:498-71-5
Package:1KG;10KG;100KG; Remarks: 纯度：根据客户需求提供
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| | SOBREROL Basic information |
| Product Name: | SOBREROL | | Synonyms: | 1-P-MENTHENE-6,8-DIOL;AURORA KA-476;SOBREROL;5-hydroxy-alpha,alpha,4-trimethylcyclohex-3-ene-1-methanol;5-Hydroxy-α,α,4-trimethyl-3-cyclohexene-1-methanol;Pinol hydrate;1-METHANE-6,8-DIOL;2-Methyl-5-(1-methyl-1-hydroxyethyl)-2-cyclohexene-1-ol | | CAS: | 498-71-5 | | MF: | C10H18O2 | | MW: | 170.25 | | EINECS: | 207-868-1 | | Product Categories: | | | Mol File: | 498-71-5.mol |  |
| | SOBREROL Chemical Properties |
| Melting point | 130°C | | Boiling point | 259.9°C (rough estimate) | | density | 0.9581 (rough estimate) | | refractive index | 1.5130 (estimate) | | pka | 14.69±0.60(Predicted) | | Water Solubility | 32g/L(15 ºC) |
| | SOBREROL Usage And Synthesis |
| Originator | Sobrepin,Corvi,Italy,1970 | | Definition | ChEBI: Sobrerol is a p-menthane monoterpenoid. | | Manufacturing Process | To 19 l of well-agitated distilled water plus 18 g of ditertiary-butyl-p-cresol
was added 19.84 kg (130 mols) of pure α-pinene oxide that was about half
racemic, half d-form. The temperature was maintained at 30°C to 50°C, first
with ice bath cooling and then with tap water cooling. The addition of the
pinene oxide required 1,5 hours. After the addition was complete and the
exothermic reaction was about over, the mixture was stirred for 2,5 hours at
about 30°C, and then centrifuged to separate the crude sobrerol from the
liquid phase consisting of oil and water.
The crude sobrerol was washed with naphtha and then air dried to yield 14.81
kg (87.5 mols) of pure sobrerol, [α]D
25 -77.0°. It was found that 1 liter of the
aqueous phase from the reaction contained 22 g of sobrerol, so, therefore, the
entire aqueous phase contained 0.42 kg (2.5 mols) of sobrerol. | | Therapeutic Function | Mucolytic |
| | SOBREROL Preparation Products And Raw materials |
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