- (R)-2-Methyl-pyrrolidine
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- $1.10 / 1g
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2022-08-20
- CAS:41720-98-3
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
- (R)-2-Methylpyrrolidine
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- $15.00 / 1KG
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2021-07-13
- CAS:41720-98-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | (R)-2-Methyl-pyrrolidine Basic information |
| | (R)-2-Methyl-pyrrolidine Chemical Properties |
| Boiling point | 94 °C(Press: 728 Torr) | | density | 0.842 | | refractive index | 1.4353 | | Fp | 45 ºF | | storage temp. | 2-8°C | | form | oil | | pka | 10.93±0.10(Predicted) | | color | Colourless to pale yellow | | Water Solubility | Insoluble in water. | | CAS DataBase Reference | 41720-98-3(CAS DataBase Reference) |
| Hazard Codes | C,F | | Risk Statements | 11-22-34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2924 | | WGK Germany | 3 | | Hazard Note | Corrosive/Highly Flammable | | HazardClass | 3 | | PackingGroup | Ⅱ | | HS Code | 29339900 |
| | (R)-2-Methyl-pyrrolidine Usage And Synthesis |
| Uses | It is used as a building block used in a multikilogram synthesis of a chiral naphthalenoid histamine receptor antagonist. | | Definition | ChEBI: (R)-2-methylpyrrolidine is a 2-methylpyrrolidine that has (R)-configuration. It is a conjugate base of a (R)-2-methylpyrrolidinium. | | Application | (R)-2-Methyl-pyrrolidine, an optically active amine that can be used as a key building block to synthesize:
4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
Naphthalenoid histamine H3 receptor antagonist.
Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2. | | References | Synthesis and structure-activity relationships of 4,5-fused pyridazinones as histamine H3 receptor antagonists. DOI:10.1016/j.bmcl.2011.08.045
Efficient and Practical Synthesis of (R)-2-Methylpyrrolidine DOI:10.1021/jo060319n
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| | (R)-2-Methyl-pyrrolidine Preparation Products And Raw materials |
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