Adenosine 5'-monophosphate monohydrate

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Products Intro: Product Name:Adenosine 5'-monophosphate monohydrate
CAS:18422-05-4
Purity:95%-99.99% Package:1KG;1USD
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Products Intro: Product Name:Adenosine-5'-monophosphoric acid (and/or unspecified salts)
CAS:18422-05-4
Purity:99% Package:5KG;1KG;25KG
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Products Intro: Product Name:Adenosine 5'-monophosphate monohydrate
CAS:18422-05-4
Purity:95% Package:1G;10G;100G Remarks:Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).
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CAS:18422-05-4
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Adenosine 5'-monophosphate monohydrate Basic information
Product Name:Adenosine 5'-monophosphate monohydrate
Synonyms:[(2R,3R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl dihydrogen phosphate;5μ-AMP, Adenylic acid from muscle, AMP;5μ-Adenylic acid, 5μ-AMP, A-5μ-P, AMP;Adenosine-5'-monophosphate(AMP),free acid;Adenosine 5′-monophosphate monohydrate,5′-AMP, 5′-Adenylic acid, A-5′-P, AMP;Adenosine-5’-phospho;5'-AMPH2;Adenosine-5'-Monophosphoric acid Monhydrate >96%
CAS:18422-05-4
MF:C10H16N5O8P
MW:365.24
EINECS:200-500-0
Product Categories:nucleoside;Nucleotides and Nucleic Acids
Mol File:18422-05-4.mol
Adenosine 5'-monophosphate monohydrate Structure
Adenosine 5'-monophosphate monohydrate Chemical Properties
Melting point 183-188 °C (dec.)(lit.)
alpha -48 º (c=2% in 2% NaOH)
FEMA 4224 | ADENOSINE MONOPHOSPHATE; MONOSODIUM, OR DISODIUM ADENYLATE
storage temp. 2-8°C
solubility H2O: with addition of mild alkalisoluble
Merck 14,158
BRN 5205540
CAS DataBase Reference18422-05-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS AU7480500
8-10-21
TSCA Yes
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Adenosine 5'-monophosphate monohydrate Usage And Synthesis
Chemical PropertiesWhite crystalline powder
UsesNutrient;Ca++ channel block
Purification MethodsThe acid has been recrystallised from H2O (fine needles) and is freely soluble in boiling H2O. It crystallises also from H2O on addition of acetone. Alternatively purify it by chromatography on Dowex 1 (in formate form), eluting with 0.25M formic acid. It is then adsorbed onto charcoal (which had been boiled for 15minutes with M HCl, washed free of chloride and dried at 100o) and recovered by stirring three times with isoamyl alcohol/H2O (1:9 v/v). The aqueous layer from the combined extracts is evaporated to dryness under reduced pressure, and the product is crystallised twice from hot H2O. [Morrison & Doherty Biochem J 79 433 1961]. It has max 259nm ( 15,400) in H2O at pH 7.0. [Alberty et al. J Biol Chem 193 425 1951, Martell & Schwarzenbach Helv Chim Acta 39 653 1956]. The acridinium salt has m 208o [Baddiley & Todd J Chem Soc 648 1947, Pettit Synthetic Nucleotides, van Nostrand-Reinhold, NY, Vol 1 252 1972, NMR: Sarma et al. J Am Chem Soc 96 7337 1974, Norton et al. J Am Chem Soc 98 1007 1976, IR of diNa salt: Miles Biochem Biophys Acta 27 324 1958]. [Beilstein 26 III/IV 3615.]
Adenosine 5'-monophosphate monohydrate Preparation Products And Raw materials
Tag:Adenosine 5'-monophosphate monohydrate(18422-05-4) Related Product Information
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