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Diclofenac potassium

Diclofenac potassium Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:Diclofenac potassium
CAS:15307-81-0
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Products Intro: Product Name:Diclofenac potassium
CAS:15307-81-0
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
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CAS:15307-81-0
Purity:99.9% Package:1KG;5USD
Company Name: career henan chemical co
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Products Intro: Product Name:Diclofenac potassium
CAS:15307-81-0
Purity:99.99% Package:1kg;1USD
Company Name: Hebei Zhuangkai Biotechnology Co.,Ltd.
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Products Intro: Product Name:Diclofenac potassium
CAS:15307-81-0
Purity:99.9% Package:100G;1USD

Lastest Price from Diclofenac potassium manufacturers

  • Diclofenac potassium
  • US $1.00 / g
  • 2021-10-18
  • CAS:15307-81-0
  • Min. Order: 1000g
  • Purity: 99%
  • Supply Ability: 20ton/month
  • Diclofenac potassium
  • US $0.00 / KG
  • 2021-10-18
  • CAS:15307-81-0
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • Diclofenac potassium
  • US $0.00-0.00 / Kg/Drum
  • 2021-09-29
  • CAS:15307-81-0
  • Min. Order: 1KG
  • Purity: 99%-101% USP
  • Supply Ability: 1000KGS
Diclofenac potassium Basic information
Description References
Product Name:Diclofenac potassium
Synonyms:PotassiuM diclofenac;ProSorb;potassium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate;Diclofenic potassiuM;Benzeneaceticacid, 2-[(2,6-dichlorophenyl)aMino]-, potassiuM salt (1:1);POTASSIUM [2-[(2,6-DICHLOROPHENYL)AMINO]PHENYL]ACETATE;DICLOFENAC POTASSIUM;DICLOFENAC POTASSIUM SALT
CAS:15307-81-0
MF:C14H10Cl2KNO2
MW:334.24
EINECS:630-422-6
Product Categories:chiral;API's;Active Pharmaceutical Ingredients;Inhibitors
Mol File:15307-81-0.mol
Diclofenac potassium Structure
Diclofenac potassium Chemical Properties
Melting point 300-330 °C
storage temp. Inert atmosphere,2-8°C
solubility Sparingly soluble in water, freely soluble in methanol, soluble in ethanol (96 per cent), slightly soluble in acetone.
form neat
CAS DataBase Reference15307-81-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,N
Risk Statements 22-51/53
Safety Statements 61
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
HS Code 2922492050
MSDS Information
Diclofenac potassium Usage And Synthesis
DescriptionDichlofenac potassium is the potassium salt of dichlofenac. It is a nonsteroidal anti-inflammatory agent that can be used to reduce inflammation and as an analgesic to reduce pain in certain conditions. It can also used to treat dysmenorrhea. It can treat inflammatory disorders such as musculoskeletal complaints, dental pain, arthritis, actinic keratosis, joint pain, acute pain and chronic pain caused by certain kinds of cancers. Traditional opinion proposes that diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency. However, recent studies have shown that the pharmacologic activity of diclofenac goes beyond COX inhibition, and includes multimodal and, in some instances, novel mechanisms of action (MOA). For example, research suggests diclofenac can inhibit the thromboxane-prostanoid receptor, affect arachidonic acid release and uptake, inhibit lipoxygenase enzymes, and activate the nitric oxide–cGMP antinociceptive pathway. Other novel MOAs may include the inhibition of substrate P, inhibition of peroxisome proliferator activated receptor gamma (PPARγ), blockage of acid-sensing ion channels, alteration of interleukin-6 production, and inhibition of N-methyl-D-aspartate (NMDA) receptor hyperalgesia.
ReferencesBrogden, R. N., et al. "Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin." Drugs 20.1 (1980): 24-48.
Gan, Tong J. "Diclofenac: an update on its mechanism of action and safety profile." Current medical research and opinion 26.7 (2010): 1715-1731.
Riihiluoma, P., E. Wuolijoki, and M. O. Pulkkinen. "Treatment of primary dysmenorrhea with diclofenac sodium." European Journal of Obstetrics & Gynecology and Reproductive Biology 12.3 (1981): 189-194.
Chemical PropertiesWhite or slightly yellowish, slightly hygroscopic, crystalline powder.
UsesCyclo-oxygenase inhibitor; analgesic; anti-inflammatory.
DefinitionChEBI: The potassium salt of diclofenac.
Brand nameCataflam (Novartis).
Diclofenac potassium Preparation Products And Raw materials
Tag:Diclofenac potassium(15307-81-0) Related Product Information
Indometacin 2,6-Dichloro-N-(4-chlorophenyl)-benzeneacetaMide Diclofenac Acyl--D-glucuronide Allyl Ester 2,4'-Dichlorobenzhydrol 1-(2,6-Dichlorophenyl)indole-2,3-dione Diclofenac Impurity 19 2-(2-Bromo-6-chlorophenyl)amino)-phenylacetic acid sodium salt 95% 2,6-DICHLORODIPHENYLAMINE 2-ANILINOPHENYLACETIC ACID 2-CHLORO-N-(2,6-DICHLOROPHENYL)ACETAMIDE DICLOFENAC-D4 (2-(2,6-DICHLOROANILINO)PHENYL) METHANOL 9H-Carbazole-1-acetic acid, 8-chloro- Diclofenac-13C6-Na hydrate (see Data Sheet) N-(2,6-dichlorophenyl)-N-phenylacetamide 2-(2,6-Dichloroanilino)-Phenylglyoxylic acid Diclofenac Impurity 7 (4-Chloro-3-hydroxyphenyl)(4-chlorophenyl)methanone