1-Benzyl-4-hydroxypiperidine

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CAS:4727-72-4
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CAS:4727-72-4
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CAS:4727-72-4
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CAS:4727-72-4
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CAS:4727-72-4
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1-Benzyl-4-hydroxypiperidine manufacturers

1-Benzyl-4-hydroxypiperidine Basic information
Product Name:1-Benzyl-4-hydroxypiperidine
Synonyms:4-HYDROXY-1-BENZYLPIPERIDINE;benzyl-4-piperidinol;4-Piperidinol, 1-(phenylmethyl)-;1-Benzyl-4-hydroxypiperidine,97%;NSC 72991;N-BENZYL-4-HYDROXYPIPERIDINE;1-(Phenylmethyl)-4-piperidinol;4-Piperidinol, 1-benzyl-
CAS:4727-72-4
MF:C12H17NO
MW:191.27
EINECS:225-226-9
Product Categories:Building Blocks;C12;Chemical Synthesis;Heterocyclic Building Blocks;Piperidines;Alcohols and Derivatives;Non-Chiral heterocyclic compounds;Agro-Products;Aromatics;Heterocycles
Mol File:4727-72-4.mol
1-Benzyl-4-hydroxypiperidine Structure
1-Benzyl-4-hydroxypiperidine Chemical Properties
Melting point 61-63 °C(lit.)
Boiling point 127-128 °C2 mm Hg(lit.)
density 1.0096 (rough estimate)
refractive index 1.5212 (estimate)
Fp 121-123°C/0.7mm
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, Methanol
pka14.87±0.20(Predicted)
form Crystalline Powder
color White to yellow
Sensitive Hygroscopic
BRN 146118
CAS DataBase Reference4727-72-4(CAS DataBase Reference)
NIST Chemistry Reference4-Piperidinol, 1-(phenylmethyl)-(4727-72-4)
Safety Information
Hazard Codes T,C,Xi,Xn
Risk Statements 25-36/37/38-20/21/22
Safety Statements 26-45-37/39-36
RIDADR UN 2811 6.1/PG 3
WGK Germany 2
HS Code 29333990
MSDS Information
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1-Benzyl-4-hydroxypiperidine Usage And Synthesis
Chemical PropertiesWHITE TO YELLOWISH CRYSTALLINE POWDER
Uses1-Benzyl-4-hydroxypiperidine was used as an alternative molecule to study the ligand concentration attached to the epoxy-activated Sepharose 6B.
Uses1-Benzyl-4-hydroxypiperidine is the reactant for synthesis of: Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist1 Fatty acid amide hydrolase inhibitors PI3 kinase-alpha inhibitors Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors Urotensin-II receptor antagonists Rho kinase inhibitors.
UsesA piperidine based pesticide
Synthesis Reference(s)Journal of the American Chemical Society, 108, p. 3512, 1986 DOI: 10.1021/ja00272a059
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