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| | ATRACTYLOSIDE POTASSIUM SALT Basic information |
| Product Name: | ATRACTYLOSIDE POTASSIUM SALT | | Synonyms: | ATR, 2K;ATRACTYLOSIDE, DIPOTASSIUM SALT;ATRACTYLOSIDE, DIPOTASSIUM SALT, ATRACTYLIS GUMMIFERA;ATRACTYLOSIDE POTASSIUM SALT;19-Norkaur-16-en-18-oic acid, 15-hydroxy-2-2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-.beta.-D-glucopyranosyloxy-, dipotassium salt, (2.beta.,15.alpha.)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]-19-norkaur-16-en-18-oic acid dipotassium salt;19-Norkaur-16-en-18-oicacid, 15-hydroxy-2-[[2-O-(3-Methyl-1-oxobutyl)-3,4-di-O-sulfo-b-D-glucopyranosyl]oxy]-,dipotassiuM salt, (2b,15a)- (9CI);Atractyloside dipotassium salt, >=98% | | CAS: | 102130-43-8 | | MF: | C30H47KO16S2 | | MW: | 766.91 | | EINECS: | | | Product Categories: | reagent;standard substance;chemical reagent;herbal extract;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Cell Stress;Mitochondrial Inhibitors;Nitric Oxide and Cell Stress | | Mol File: | 102130-43-8.mol |  |
| | ATRACTYLOSIDE POTASSIUM SALT Chemical Properties |
| Melting point | 234-238°C | | storage temp. | Sealed in dry,2-8°C | | solubility | H2O: 20 mg/mL | | form | Solid | | color | Pale Brown to Pale Beige | | Stability: | Hygroscopic |
| Hazard Codes | T | | Risk Statements | 23/24/25 | | Safety Statements | 36/37-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | HazardClass | 6.1(a) | | PackingGroup | I | | HS Code | 2938909090 |
| | ATRACTYLOSIDE POTASSIUM SALT Usage And Synthesis |
| Description | Atractyloside is a natural heteroglucoside produced in some plants, including A. gummifera. Atractyloside prevents mitochondrial ATP synthesis by inhibiting ADP/ATP translocases, which are responsible for the exchange of adenine di- and triphosphates across the inner mitochondrial membrane. | | Uses | Atractyloside Dipotassium Salt is an inhibitor of ANT and apoptosis inducer. | | references | [1]. yamaguchi n, kagari t, kasai m. inhibition of the ryanodine receptor calcium channel in the sarcoplasmic reticulum of skeletal muscle by an adp/atp translocase inhibitor, atractyloside. biochem biophys res commun, 1999, 258(2): 247-251.
[2]. pick-kober kh, schneider f. proliferation, macromolecular synthesis and energy metabolism of in vitro grown ehrlich ascites tumor cells after inhibition of atp-adp translocation by atractyloside. eur j cell biol, 1984, 34(2): 323-329.
[3]. malekova l, kominkova v, ferko m, et al. bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart. biochim biophys acta, 2007, 1767(1): 31-44. |
| | ATRACTYLOSIDE POTASSIUM SALT Preparation Products And Raw materials |
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