| Company Name: |
Jinan Kabotang Biological Technology Co.,Ltd.
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| Tel: |
0531-61320525 15866703830 |
| Email: |
figo.gao@foxmail.com |
| Products Intro: |
Product Name:(2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE
CAS:1584647-27-7
Purity:98% HPLC Package:1kg
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| Company Name: |
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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| Tel: |
025-025-66113011 18626450290 |
| Email: |
cb5@aikonchem.com |
| Products Intro: |
Product Name:(2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE
CAS:1584647-27-7
Purity:95% Package:1g;5g;10g
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Notch inhibitor 1
CAS:1584647-27-7
Package:100mg/RMB 33500;50mg/RMB 25800;25mg/RMB 19400
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| | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE Basic information |
| Product Name: | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE | | Synonyms: | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE;NOTCH INHIBITOR 1;Butanediamide, N1-[(3S)-5-(3-fluorophenyl)-2,3-dihydro-9-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl)-, (2R,3S)- | | CAS: | 1584647-27-7 | | MF: | C26H25F7N4O3 | | MW: | 574.49 | | EINECS: | | | Product Categories: | | | Mol File: | 1584647-27-7.mol | ![(2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE Structure](CAS/20180601/GIF/1584647-27-7.gif) |
| | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE Chemical Properties |
| Boiling point | 714.9±60.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | pka | 11.67±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE Usage And Synthesis |
| Uses | BMS-986115 (Notch inhibitor 1) is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1]. | | References | [1] Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1. |
| | (2R,3S)-N1-((S)-5-(3-FLUOROPHENYL)-9-METHYL-2-OXO-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-2,3-BIS(3,3,3-TRIFLUOROPROPYL)SUCCINAMIDE Preparation Products And Raw materials |
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