| Company Name: |
Borenpharm Co., Ltd
|
| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:I-PEG5-OH
MFCD31656975
CAS:1883516-31-1
Purity:95% HPLC Package:1g; 5g
|
| Company Name: |
Amatek Scientific Co. Ltd.
|
| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:I-PEG5-OH
CAS:1883516-31-1
Purity:97% HPLC Package:1g;5g;25g;100g
|
|
| | I-PEG5-OH Basic information |
| Product Name: | I-PEG5-OH | | Synonyms: | I-PEG5-OH;I-PEG5-OH
MFCD31656975;I-PEG5-OH/3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo-;3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo- | | CAS: | 1883516-31-1 | | MF: | C10H21IO5 | | MW: | 348.18 | | EINECS: | | | Product Categories: | | | Mol File: | 1883516-31-1.mol |  |
| | I-PEG5-OH Chemical Properties |
| Boiling point | 382.0±37.0 °C(Predicted) | | density | 1.479±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | I-PEG5-OH Usage And Synthesis |
| Biological Activity | I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | I-PEG5-OH Preparation Products And Raw materials |
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