ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Crown ether >DOTA

DOTA

DOTA Suppliers list
Company Name: HAINAN POLY PHARMCEUTICAL CO. LTD
Tel: +86-0571-89385087 +8613616530509
Email: ff@hnpoly.com
Products Intro: Product Name:1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA)
CAS:60239-18-1
Purity:Intermediate Package:1g;10g;1kg;25kg Remarks:Pharmaceutical
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:DOTA
CAS:60239-18-1
Purity:99% Package:25KG
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177
Email: peter@yan-xi.com
Products Intro: Product Name:DOTA
CAS:60239-18-1
Purity:0.99 Package:1kg;10USD|100kg;6USD|1000kg;1USD Remarks:Factory direct sales
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:DOTA
CAS:60239-18-1
Purity:99% Package:25KG;5KG;1KG
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:DOTA
CAS:60239-18-1
Purity:98% Package:1KG;1USD

DOTA manufacturers

  • DOTA
  • DOTA pictures
  • $10.00 / 1kg
  • 2023-09-07
  • CAS:60239-18-1
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 30 tons
  • DOTA
  • DOTA pictures
  • $0.00 / 1KG
  • 2023-09-06
  • CAS:60239-18-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500000kg
  • DOTA
  • DOTA pictures
  • $0.00 / 25KG
  • 2023-07-29
  • CAS:60239-18-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
DOTA Basic information
Product Name:DOTA
Synonyms:TETRAAZA-12-CROWN-4 TETRAACETIC ACID AMMONIUM SALT (SEE 2923);Tetraxetan/radical;1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrakisacetic acid;2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetraacetic acid;2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetrakisacetic acid;1,4,7,10-TETRAAZACYCLODODECANE-N,N'',N , N''-TETRAACETIC ACID , (DOTA);1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID DOTA;DOTA(M-140)
CAS:60239-18-1
MF:C16H28N4O8
MW:404.42
EINECS:611-959-5
Product Categories:Achiral Nitrogen;Cy-N;Azacrown Ethers;Functional Materials;Macrocycles for Host-Guest Chemistry;60239-18-1
Mol File:60239-18-1.mol
DOTA Structure
DOTA Chemical Properties
Melting point 267 °C
Boiling point 701.6±60.0 °C(Predicted)
density 1.321
storage temp. Sealed in dry,Room Temperature
solubility Water (Slightly, Heated), Methanol (Slightly)
pka2.16±0.10(Predicted)
form Powder
color white
BRN 1186987
Stability:Hygroscopic
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
3-10-34
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
DOTA Usage And Synthesis
Chemical PropertiesColourless crystals
UsesBifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and ther apeutic radiopharmaceuticals.
Uses1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent.
  • It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64Cu radioisotope.
  • DOTA can be activated with N-hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.
  • It can form complexes with gadolinium for application as MRI contrast agents.
  • Metal complexes of DOTA-peptide conjugates can be used as therapeutic radiopharmaceuticals.

DefinitionChEBI: An azamacrocyle in which four nitrogen atoms at positions 1, 4, 7 and 10 of a twelve-membered ring are each substituted with a carboxymethyl group.
Tag:DOTA(60239-18-1) Related Product Information
1,4,7,10-Tetrakis(ethoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane DOTA Gadoteric acid 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 2-[(4-isothiocyanatophenyl)methyl]- TETRYL 12-Crown-4 Eu-DOTA,Europium DOTA TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD GADOMELITOL DOTA-[TYR3]-OCTREOTATE,DOTA-[TYR3]-OCTREOTIDE ACID,DOTA-FCYWKTCT (DISULFIDE BRIDGE: 2-7),DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OH (DISULFIDE BRIDGE: 2-7) DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL (DISULFIDE BRIDGE: 2-7) gadolinium DOTA meglumine DOTA-BIM-23014:DOTA-Lanreotide,DOTA-Lanreotide DOTA-(Tyr3)-Octreotate Iron DOTA Sodium Salt DOTA-glycyl-glycyl-glycyl-(4-nitrophenyl)alanine amide DOTA-NOC, DOTA-[Nal3]-octreotide,DOTA-NOC yttrium-90-DOTA-peptide-chimeric L6