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Finasteride

Finasteride Suppliers list
Company Name: Shanghai Payne Pharmaceutical Technology Co.Ltd
Tel: 021-58123769
Email: info@paynepharm.com
Products Intro: Product Name:Finasteride
CAS:98319-26-7
Purity:99% HPLC Package:1G;50G;100G;1KG
Company Name: Beijing Yibai Biotechnology Co., Ltd
Tel: 0086-182-6772-3597
Email: sales01@yibaibiotech.com
Products Intro: Product Name:Finasteride
CAS:98319-26-7
Purity:99%+ Package:1g;USD|10g;USD|100g;USD|500g;USD|1KG;USD
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Finasteride
CAS:98319-26-7
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd.
Tel: +86-10-60279497 +86(0)15646567669
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:FINASTERIDE
CAS:98319-26-7
Purity:98% Package:100G;1KG;50KG;100KG;1000KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:98319-26-7
CAS:98319-26-7
Purity:0.99 Package:25KG,5KG;1KG;500G

Lastest Price from Finasteride manufacturers

  • Finasteride
  • US $0.00-0.00 / KG
  • 2020-01-18
  • CAS:98319-26-7
  • Min. Order: 1g
  • Purity: 99%+
  • Supply Ability: 25kg/month
  • finasteride
  • US $60.00 / KG
  • 2019-11-05
  • CAS:98319-26-7
  • Min. Order: 10g
  • Purity: 99.8%
  • Supply Ability: 10tons
  • Finasteride
  • US $1.00 / g
  • 2019-07-31
  • CAS:98319-26-7
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100 Kilogram/Kilograms per Month
Finasteride Basic information
Indications and Usage Mechanisms of Action
Product Name:Finasteride
Synonyms:(1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-N-(2-methylpropyl)-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta;l-652,931;mk-0906;n-tert-butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide;1,(5-ALPHA)-ANDROSTAN-4-AZA-3-ONE-17-BETA-(N-TERT-BUTYL-CARBOXAMIDE)
CAS:98319-26-7
MF:C23H36N2O2
MW:372.54
EINECS:620-534-3
Product Categories:Intracellular receptor;Steroid and Hormone;Active Pharmaceutical Ingredients;API;Biochemistry;PROSCAR;Steroids;Steroids (Others);Intermediates & Fine Chemicals;Pharmaceuticals;Vitamin Ingredients;Hormone Drugs
Mol File:98319-26-7.mol
Finasteride Structure
Finasteride Chemical Properties
Melting point 253 °C
alpha 405 -59° (c = 1 in methanol)
Boiling point 576.6±50.0 °C(Predicted)
density 1.065±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: 32 mg/mL, soluble
pka14.17±0.70(Predicted)
form solid
color white to beige
Water Solubility insoluble
Merck 14,4082
InChIKeyDBEPLOCGEIEOCV-WSBQPABSSA-N
CAS DataBase Reference98319-26-7(CAS DataBase Reference)
EPA Substance Registry System1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- (98319-26-7)
Safety Information
Hazard Codes Xn,T,Xi
Risk Statements 22-61-60-36/37/38
Safety Statements 36/37/39-45-53-36-26-24/25
WGK Germany 3
RTECS CL5245000
HS Code 29379000
Hazardous Substances Data98319-26-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
Finasteride Usage And Synthesis
Indications and UsageFinasteride is a basic drug to treat benign prostatic hyperplasia and prostatitis, a synthetic 4-nitrogen steroid hormone compound and a sex hormone drug.
It is used for benign prostatic hyperplasia, men's prostatic fat and other diseases. Finasteride is the only oral drug approved by the US Food and Drug Administration (FDA) to treat male pattern baldness.
Mechanisms of ActionFinasteride can selectively inhibit 5α-reductase, changing the conversion process of testosterone into 5α dihydrotestosterone (DHT), decreasing androgen levels in prostate cells, and prostate-specific antigens in serum, decreasing prostate swelling, and increasing urine flow rate, thereby alleviating the symptoms of prostatic hyperplasia. It acts by selectively blocking androgen stimulation of the prostate, but affects sexual function very rarely. Meanwhile, due to blocking of testosterone conversion and reduced synthesis of dihydrotestosterone, it can reduce dihydrotestosterone levels in the serum and scalp hair follicles, recovering the function of previously inhibited hair follicles, promoting hair growth and preventing loss.
DescriptionFinasteride, a novel 4-azasteroid, is a breakthrough in the treatment and control of benign prostatic hyperplasia. Mechanistically, it inhibits the prostatic-specific enzyme 5-alpha reductase, thereby decreasing the conversion of testosterone to dihydrotestosterone. It is reportedly effective in reducing urinary symptoms and prostatic volume and increasing maximal urinary flow rate. Finasteride is also being investigated as a treatment for prostatic cancer.
Chemical PropertiesOff-White Crystalline Powder
OriginatorMerck (U.S.A.)
UsesInhibitor of 5a-reductase, the enzyme which converts testosterone to the more potent androgen, 5a-dihydrotestosterone. Antialopecia agent
UsesInhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone. Antialopecia agent.
Usesanti-androgen, alpha-reductase inhibitor
UsesTreatment of benign prostatic hyperplasia and androgenetic alopecia
DefinitionChEBI: An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.
IndicationsFinasteride (Proscar) is a 5-reductase inhibitor that blocks the conversion of testosterone to DHT in target tissues. Since DHT is the major intracellular androgen in the prostate, finasteride is effective in suppressing DHT stimulation of prostatic growth and secretory function without markedly affecting libido. It is approved for the treatment of benign prostatic hyperplasia. Although there is usually some regression in the size of the prostate gland following administration of finasteride, clinical response may take 6 to 12 months. If the obstructive symptoms are severe, there is often not enough time to allow this compound to work.The principal adverse effects of finasteride are impotence, decreased libido, and decreased volume of ejaculate. The compound is generally well tolerated in men.
Brand nameProscar
Biological ActivityAntiandrogen that inhibits type II 5 α reductase (IC 50 = 65 nM). Suppresses the conversion of testosterone to dihydrotestosterone. Reduces prostatic dihydrotestosterone levels and prostate size in vivo . Orally active.
Veterinary Drugs and TreatmentsFinasteride may be useful in treating the benign prostatic hypertrophy in canine patients. Because of the drug’s relative expense and the long duration of therapy required to see a response, its usefulness may be limited in veterinary medicine.
It may also be useful in the adjunctive treatment of adrenal disease in ferrets.
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