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Cephalothin

Cephalothin Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Cephalothin
CAS:58-71-9
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:58-71-9
CAS:58-71-9
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:cephalothin sodium
CAS:58-71-9
Purity:99% Package:5KG;1KG Remarks:C16H15N2NaO6S2
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 592-605 1114
Email: sales@amoychem.com
Products Intro: Product Name:Cefalotin Sodium
CAS:58-71-9
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:Cephalothin
CAS:58-71-9
Purity:0.99 Package:5KG;1KG

Lastest Price from Cephalothin manufacturers

  • Cephalothin
  • US $0.00-0.00 / 公斤
  • 2020-05-25
  • CAS:58-71-9
  • Min. Order: 1公斤
  • Purity: 99.0%+
  • Supply Ability: 300 MT
  • Cephalothin
  • US $3.00 / KG
  • 2020-01-08
  • CAS:58-71-9
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 200KG
Cephalothin Basic information
Product Name:Cephalothin
Synonyms:Cefalotin Sodium(Sterile);Cefalotin Free acid;CEPHALOTIN ACID;3-(Hydroxymethyl)-8-oxo-7-(2-[2-thienyl] acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid acetate;7-(Thiophene-2-acetamido) cephalosporanic acid;Microtin;Sodium keflin;5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(acetyloxy)methyl-8-oxo-7-(2-thienylacetyl)amino-, monosodium salt, (6R,7R)-
CAS:58-71-9
MF:C16H15N2NaO6S2
MW:418.42
EINECS:200-394-6
Product Categories:Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;antibiotic
Mol File:58-71-9.mol
Cephalothin Structure
Cephalothin Chemical Properties
Melting point 240°C
alpha D +135° (c = 1.0 in water)
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear, faintly yellow
form neat
Water Solubility 158 mg/L
Merck 13,1994
BRN 4120706
CAS DataBase Reference58-71-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 42/43
Safety Statements 22-36/37
WGK Germany 2
RTECS XI0388300
HS Code 29419000
ToxicityLD50 in mice, rats (mg/kg): >20000, >10000 orally; 5670, 7716 i.p. (Kuramoto)
MSDS Information
Cephalothin Usage And Synthesis
Chemical PropertiesCrystalline
UsesAntibacterial;Bacterial transpeptidase inhibitor
UsesCephalothin is a first-generation cephalosporin antibiotic used to study the mechanism of liposome encapsulated antibiotics,strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics,and for immunology studies in relation to antibiotics.It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.
Brand nameKeflin (Lilly); Seffin (GlaxoSmithKline).
Clinical UseCephalothin sodium (Keflin) occurs as a white to off-white,crystalline powder that is practically odorless. It is freelysoluble in water and insoluble in most organic solvents.Although it has been described as a broad-spectrum antibacterialcompound, it is not in the same class as the tetracyclines.Its spectrum of activity is broader than that ofpenicillin G and more similar to that of ampicillin. Unlikeampicillin, cephalothin is resistant to penicillinase producedby S. aureus and provides an alternative to the use ofpenicillinase-resistant penicillins for the treatment of infectionscaused by such strains.
Cephalothin is absorbed poorly from the GI tract andmust be administered parenterally for systemic infections. It is relatively nontoxic and acid stable. It is excreted rapidlythrough the kidneys; about 60% is lost within 6 hours of administration.Pain at the site of intramuscular injection andthrombophlebitis following intravenous injection have beenreported. Hypersensitivity reactions have been observed,and there is some evidence of cross-sensitivity in patientsnoted previously to be penicillin sensitive.
Cephalothin Preparation Products And Raw materials
Raw materialsSodium acetate trihydrate-->Butyl acetate-->7-Aminocephalosporanic acid-->7-(5-amino-5-carboxyvaleramido)cephalosporanic acid
Preparation ProductsCefuroxime
Tag:Cephalothin(58-71-9) Related Product Information
METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE 7-AMCA 2-Acetamidoacrylic acid Methallyl acetate 2-Thiophenemethylamine METHALLYL MERCAPTAN 2-(METHYLTHIO)METHYL-2-BUTENOL sodium Thifensulfuron methyl Trisodium phosphate Tetrahydrothiophene Sodium chloride (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid Sodium citrate Sodium alginate 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Sodium benzoate Thiophene