- 1,2,3,4-Tetrahydrocarbazole
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- $15.00 / 1KG
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2021-07-02
- CAS:942-01-8
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 1,2,3,4-Tetrahydrocarbazole Basic information |
| Product Name: | 1,2,3,4-Tetrahydrocarbazole | | Synonyms: | ,3,4,9-Tetrahydro-1H-carbazole;1H-Indole, 2,3-(1,4-butanediyl)-;2,3,4,9-tetrahydro-1h-carbazol;2,3-Tetramethylene-1H-indole;5,6,7,8-tetrahydro-carbazol;5,6,7,8-Tetrahydrocarbazole;Carbazole, 1,2,3,4-tetrahydro-;Carbazole, 5,6,7,8-tetrahydro- | | CAS: | 942-01-8 | | MF: | C12H13N | | MW: | 171.24 | | EINECS: | 213-385-7 | | Product Categories: | Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Building Blocks;Carbazoles;Heterocyclic Building Blocks | | Mol File: | 942-01-8.mol |  |
| | 1,2,3,4-Tetrahydrocarbazole Chemical Properties |
| Melting point | 118-120 °C (lit.) | | Boiling point | 325-330 °C (lit.) | | density | 1.1459 (rough estimate) | | refractive index | 1.6544 (estimate) | | Fp | 325-330°C | | storage temp. | Sealed in dry,Room Temperature | | pka | 17.84±0.20(Predicted) | | form | powder to crystal | | color | White to Orange to Green | | Water Solubility | Insoluble in water. Solubility in methanol (almost transparency). | | BRN | 133771 | | CAS DataBase Reference | 942-01-8(CAS DataBase Reference) | | NIST Chemistry Reference | 1H-Carbazole, 2,3,4,9-tetrahydro-(942-01-8) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 2 | | RTECS | FE6300000 | | HS Code | 29339900 |
| | 1,2,3,4-Tetrahydrocarbazole Usage And Synthesis |
| Chemical Properties | beige crystalline powder | | Uses | 1,2,3,4-Tetrahydrocarbazole can be used as a starting material to prepare:
- Spiro[cyclopentane-1,2′-indolin-3′-one] by photooxygenation.
- 9-Acyl-1,2,3,4-tetrahydrocarbazoles by N-acylation reactions.
- Carbazole via palladium-catalyzed asymmetric hydrogenation reaction.
| | Uses | It finds its application as a pharmaceutical intermediate and in the synthesis of aspidospermidine alkaloids. | | Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 14, p. 934, 1966 DOI: 10.1248/cpb.14.934
Tetrahedron Letters, 26, p. 161, 1985 DOI: 10.1016/S0040-4039(00)61869-5 |
| | 1,2,3,4-Tetrahydrocarbazole Preparation Products And Raw materials |
| Preparation Products | Ondansetron-->1,2,3,9-Tetrahydro-4(H)-carbazol-4-one-->9-[(5-chloro-1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)ethylidene]-2,3,4,4a,9,9a-hexahydro-1H-carbazolium chloride-->9-METHYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE |
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