LIT-927

LIT-927 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:LIT-927
CAS:2172879-52-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Chemia Biotechnology(Shanghai) Co., Ltd
Tel: +8613816753574
Email: info@chemia-pharm.com
Products Intro: Product Name:LIT-927
CAS:2172879-52-4
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:LIT-927
CAS:2172879-52-4
Purity:99% Package:5KG;1KG Remarks:LIT-927
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:LIT-927
CAS:2172879-52-4
Purity:98% Package:5mg Remarks:V4031
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:LIT927;LIT-927;LIT 927
CAS:2172879-52-4
Package:1 mL * 10mM (in DMSO);10 mg;100 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
LIT-927 Basic information
Product Name:LIT-927
Synonyms:CS-2869;LIT-927;2(1H)-Pyrimidinone, 4-(4-chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)-;4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one
CAS:2172879-52-4
MF:C17H13ClN2O3
MW:328.75
EINECS:
Product Categories:API
Mol File:2172879-52-4.mol
LIT-927 Structure
LIT-927 Chemical Properties
storage temp. Store at -20°C
solubility DMSO:66.0(Max Conc. mg/mL);200.76(Max Conc. mM)
form A solid
color Light yellow to yellow
Safety Information
MSDS Information
LIT-927 Usage And Synthesis
Biochem/physiol ActionsLIT-927 is an orally active CXCL12 (SDF1) neutraligand (Kd = 267) that selectively neutralizes CXCL12, but not CCL17, CCL22, CCL5, or CCL2 activity in cultures (10 μM LIT-927 against 5 nM chemokine-induced calcium mobilization). LIT-927 reduces eosinophil recruitment in a murine allergic airway hypereosinophilia model in vivo (330 nmol/kg intranasal, 350 nmol/kg ip. or 1400 μmol/kg po.), offering greatly improved oral activity and solubility than Chalcone-4, and exhibiting little side-effects when compared with dexamethasone or CXCR4 antagonist AMD3100.
LIT-927 Preparation Products And Raw materials
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