- Pivalic anhydride
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- $13.00 / 1kg
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2024-01-24
- CAS:1538-75-6
- Min. Order: 1kg
- Purity: 99.0%
- Supply Ability: 1000MT
- TRIMETHYLACETIC ANHYDRIDE
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- $50.00 / 1KG
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2023-12-23
- CAS:1538-75-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | Trimethylacetic anhydride Basic information |
| Product Name: | Trimethylacetic anhydride | | Synonyms: | 2,2-DIMETHYLPROPIONIC ANHYDRIDE;2,2-Dimethylpropionic anhydride, Pivalic anhydride;Bis(2,2-dimethylpropionic acid)anhydride;Bis(pivalic acid)anhydride;Dipivalic anhydride;Trimethylacetic anhydride,99%;Propanoic acid, 2,2-dimethyl-, anhydride;Propanoicacid,2,2-dimethyl-,anhydride | | CAS: | 1538-75-6 | | MF: | C10H18O3 | | MW: | 186.25 | | EINECS: | 216-263-1 | | Product Categories: | Aliphatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aliphatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 1538-75-6.mol |  |
| | Trimethylacetic anhydride Chemical Properties |
| Boiling point | 193 °C(lit.) | | density | 0.918 g/mL at 25 °C(lit.) | | vapor pressure | 62.1Pa at 25℃ | | refractive index | n20/D 1.409(lit.) | | Fp | 135 °F | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Miscible with acetonitrile. | | form | Liquid | | color | Clear colorless | | Sensitive | Moisture Sensitive | | BRN | 386552 | | InChI | InChI=1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3 | | InChIKey | PGZVFRAEAAXREB-UHFFFAOYSA-N | | SMILES | C(C)(C)(C)C(=O)OC(=O)C(C)(C)C | | LogP | 2.15 | | CAS DataBase Reference | 1538-75-6(CAS DataBase Reference) | | EPA Substance Registry System | Propanoic acid, 2,2-dimethyl-, anhydride (1538-75-6) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2920 8/PG 2 | | WGK Germany | 3 | | F | 9-13-21 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29159000 |
| | Trimethylacetic anhydride Usage And Synthesis |
| Description | Trimethylacetic anhydride is a pivalic acid derivative that is used in organic synthesis. The compound's reaction mechanism is believed to be the formation of an alkanoic acid, which reacts with a hydroxyl group to form an anhydride. Trimethyl acetic anhydride has been shown to have pharmacokinetic properties and can be used as a nonsteroidal anti-inflammatory drug. This compound has also been found to have a matrix effect on crystalline cellulose and is capable of forming nitrogen-containing carboxylic acids. | | Chemical Properties | clear colourless liquid | | Uses | Trimethylacetic anhydride was used:
- in solid-phase oligonucleotide synthesis
- in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
- as acylation and esterification reagent for anilines
- as acylation and esterification reagent for phenols
| | Uses | A metabolite of a double prodrug (6-dGCV-DPiv | | Flammability and Explosibility | Not classified |
| | Trimethylacetic anhydride Preparation Products And Raw materials |
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