N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride

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N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Basic information
Product Name:N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride
Synonyms:BENZYLOXYCARBONYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE;Z-ARG-ARG-MCA HYDROCHLORIDE;Z-ARG-ARG-MCA(HYDROCHLORIDE FORM);Z-ARG-ARG-AMC HYDROCHLORIDE SALT;benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide;Z-Arg-Arg-NHMec;L-Argininamide, N2-[(phenylmethoxy)carbonyl]-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-1-oxopentan-2-yl]carbamate
CAS:88937-61-5
MF:C30H39N9O6
MW:621.69
EINECS:
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Mol File:88937-61-5.mol
N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Structure
N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Chemical Properties
density 1.41±0.1 g/cm3(Predicted)
storage temp. −20°C
pka11.01±0.46(Predicted)
SequenceZ-Arg-Arg-{AMC}
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
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N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Usage And Synthesis
UsesZ-Arg-Arg-AMC is a selective substrate of cathepsin B[1].
References[1] Hulkower KI, et, al. Fluorescent microplate assay for cancer cell-associated cathepsin B. Eur J Biochem. 2000 Jul;267(13):4165-70. DOI:10.1046/j.1432-1327.2000.01458.x
N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Preparation Products And Raw materials
Tag:N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride(88937-61-5) Related Product Information
Na-Cbz-Arg-Arg 4-methoxy-β-naphthylamide Z-Arg-Leu-Arg-Gly-Gly-AMC Z-Arg-AMC HCl Z-Arg-Arg-Arg-4m-betana acetate salt Z-Arg-Arg-4-methoxy-2-naphthylamine Z-Arg-Arg-7-amino-4-trifluoromethylcoumarin N-alpha-Cbz-Arg-Arg-Pro-Phe-His-Sta-Ile-His-N-epsilon-Boc-Lys methyl ester N-alpha-Cbz-Arg-Arg 7-amido-4-methylcoumarin hydrochloride Z-Arg-AMC CATHEPSIN B SUBSTRATE I, COLORIMETRIC BML-244 Z-Phe-Arg-pNA L(+)-Arginine