Genz 669178 (Genz669178)

Genz 669178 (Genz669178) Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:Genz-669178 CAS:1254834-91-7 Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel:	86-571-88216897,88216896 13588875226
Email:	sales@hzclap.com
Products Intro:	Product Name:Genz 669178 CAS:1254834-91-7 Purity:59899% Package:10kg 25kg 200 kilograms per barrel Remarks:good

Company Name:	TargetMol Chemicals Inc.
Tel:	+17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:Genz-669178 CAS:1254834-91-7 Package:50mg;1980USD\|25mg;1520USD\|100mg;2500USD

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:Genz-669178 CAS:1254834-91-7 Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500

Company Name:	Nanjing Shizhou Biology Technology Co.,Ltd
Tel:	025-85560043 15850508050
Email:	cindy.huang@synzest.com
Products Intro:	Product Name:Genz 669178 CAS:1254834-91-7 Purity:98% Package:10mg 100mg

Genz 669178 (Genz669178) manufacturers

Genz 669178 (Genz669178) Basic information

Product Name:	Genz 669178 (Genz669178)
Synonyms:	Genz 669178 (Genz669178);Genz 669178;2-Thiophenecarboxamide, 5-(4-cyano-2-methyl-1H-benzimidazol-1-yl)-N-cyclopropyl-
CAS:	1254834-91-7
MF:	C17H14N4OS
MW:	322.38
EINECS:
Product Categories:
Mol File:	1254834-91-7.mol

Genz 669178 (Genz669178) Chemical Properties

Safety Information

MSDS Information

Genz 669178 (Genz669178) Usage And Synthesis

Description	Genz-669178 is a wild-type Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor.
Uses	Genz-669178 is an inhibitor for dihydroorotate dehydrogenase (DHODH) with IC50 of 0.015-0.05 μM in Plasmodium spp.. Genz-669178 inhibits P. berghei, P. falciparum strains 3D7 and Dd2 with IC50 of 0.068, 0.008 and 0.01 μM, respectively. Genz-669178 exhibits anti-malarial efficacy in P. berghei-infected mice with ED50 of 13-21 mg/kg/day. Genz-669178 exhibits good pharmacokinetic characteristics in mice[1].
References	[1] Booker ML, et al., Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model. J Biol Chem. 2010 Oct 22;285(43):33054-33064. DOI:10.1074/jbc.M110.162081

Genz 669178 (Genz669178) Preparation Products And Raw materials

Tag:Genz 669178 (Genz669178)(1254834-91-7) Related Product Information

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.