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4-BROMO-A23187

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:4-Bromo A23187；4-?Bromo A23187
CAS:76455-48-6
Purity:98.00% Package:1 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: BOC Sciences
Tel: +16314854226
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Products Intro: Product Name:4-Bromo-A23187
CAS:76455-48-6
Purity:>=98% Remarks:BOC Sciences also provides custom synthesis services for 4-Bromo-A23187.
Company Name: Shanghai Acmec Biochemical Technology Co., Ltd.
Tel: +undefined18621343501
Email: product@acmec-e.com
Products Intro: Product Name:4-Bromo A23187
CAS:76455-48-6
Purity:98% Package:1mg
Company Name: J & K SCIENTIFIC LTD.  
Tel: 010-82848833 400-666-7788
Email: jkinfo@jkchemical.com
Products Intro: Product Name:4-Bromo-calcium ionophore A23187
CAS:76455-48-6
Package:1MG;5MG
Company Name: Syntechem Co.,Ltd  
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Products Intro: Product Name:6-broMo-5-(MethylaMino)-2-(((2R,3R,6S,8S,9R,11R)-3,9,11-triMethyl-8-((S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)Methyl)benzo[d]oxazole-4-carboxylic acid
CAS:76455-48-6
Purity:97% Package:1g;5g;25g;100g;250g;1kg;5kg;10kg;25kg Remarks:we offer low price custom synthesis and contract manufacturing
4-BROMO-A23187 Basic information
Product Name:4-BROMO-A23187
Synonyms:ANTIBIOTIC A-23187, 4-BROMO;CALCIMYCIN, 4-BROMO;4-BROMO-A23187;4-BROMO-ANTIBIOTIC;4-BROMO-ANTIBIOTIC A23187;4-BROMOCALCIMYCIN;4-BROMOCALCIMYCIN A23187;4-BROMO-CALCIUM IONOPHORE A23187
CAS:76455-48-6
MF:C29H36BrN3O6
MW:602.52
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Mol File:76455-48-6.mol
4-BROMO-A23187 Structure
4-BROMO-A23187 Chemical Properties
Boiling point 735.4±60.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility ethanol: 20 mg/mL
pka15.14±0.50(Predicted)
form powder
color yellow
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37/39-36/37
WGK Germany 3
HS Code 29419090
MSDS Information
ProviderLanguage
SigmaAldrich English
4-BROMO-A23187 Usage And Synthesis
Chemical PropertiesYellow powder
Uses4-Bromo-A23187 is an ionophore that transports Zn2+ and Mn2+ with high selectivity over Ca2+.
Uses4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca2+/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells.
Biochem/physiol Actions4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca2+ levels.
4-BROMO-A23187 Preparation Products And Raw materials
Tag:4-BROMO-A23187(76455-48-6) Related Product Information
2-AMINO-3-BROMOBENZOIC ACID 2-Acetyl pyrrole 2-ETHYL-BENZOOXAZOLE 1,7-DIOXASPIRO[5.5]UNDECANE A23187 2-PROPIONYLPYRROLE 4-ISOBUTOXY-2-BUTANONE 6-BROMOBENZOXAZOLE 2-BROMO-6-METHYLANILINE 5-AMINOBENZOOXAZOLE 6-BROMO-2-METHYLBENZODOXAZOLE 2-ETHYL-1,3-BENZOXAZOL-5-AMINE 4-BROMO-A23187 2-METHYL-1,3-BENZOXAZOL-5-AMINE 1,1-DI(2-METHYLBUTOXY)ETHANE 1,1-DI-ISOBUTOXYPROPANE 4-SEC-BUTOXY-2-BUTANONE 2-BUTYL-1,3-BENZOXAZOL-5-AMINE