|
|
| | SORAFENIB N-OXIDE Basic information |
| Product Name: | SORAFENIB N-OXIDE | | Synonyms: | SORAFENIB N-OXIDE;4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-2-pyridinecarboxaMide 1-Oxide;Sorafenib impurity 23/Sorafenib N-Oxide/4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide;Sorafenib Impurity 27(Sorafenib N-Oxide);2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 1-oxide;4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide;Sorafenib impurities172;Sorafenib impurities11 | | CAS: | 583840-03-3 | | MF: | C21H16ClF3N4O4 | | MW: | 480.82 | | EINECS: | | | Product Categories: | Metabolites;Various Metabolites and Impurities | | Mol File: | 583840-03-3.mol |  |
| | SORAFENIB N-OXIDE Chemical Properties |
| Melting point | 220-222oC | | Boiling point | 591.7±50.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO: soluble; Methanol: very slightly soluble, heated | | form | A solid | | pka | 12.89±0.70(Predicted) |
| | SORAFENIB N-OXIDE Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | A metabolite of Sorafenib, a potent Raf kinase inhibitor. |
| | SORAFENIB N-OXIDE Preparation Products And Raw materials |
|