Taurohyodeoxycholic acid sodium salt hydrate manufacturers
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| | Taurohyodeoxycholic acid sodium salt hydrate Basic information |
| Product Name: | Taurohyodeoxycholic acid sodium salt hydrate | | Synonyms: | Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate;5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDE | | CAS: | 38411-85-7 | | MF: | C26H46NNaO6S | | MW: | 523.7 | | EINECS: | | | Product Categories: | | | Mol File: | 38411-85-7.mol |  |
| | Taurohyodeoxycholic acid sodium salt hydrate Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml | | form | A crystalline solid |
| | Taurohyodeoxycholic acid sodium salt hydrate Usage And Synthesis |
| Description | Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis. | | Uses | Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions. | | General Description | Sodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent. |
| | Taurohyodeoxycholic acid sodium salt hydrate Preparation Products And Raw materials |
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Tag:Taurohyodeoxycholic acid sodium salt hydrate(38411-85-7)
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