DELTORPHIN I
| 中文名称 | DELTORPHIN I |
|---|---|
| 中文同义词 | 化合物DELTORPHIN I(TFA);D-ALA2] DELTORPHIN I-新皮啡肽 |
| 英文名称 | DELTORPHIN I |
| 英文同义词 | tyr-D-ala-phe-asp-val-val-gly amide;M.W. 768.87 C37H52N8O10;L-Tyr-D-Ala-L-Phe-L-Asp-L-Val-L-Val-Gly-NH2;L-Tyr-D-Ala-L-Phe-L-αAsp-L-Val-L-Val-Gly-NH2;Delt-i;Glycinamide, L-tyrosyl-D-alanyl-L-phenylalanyl-L-alpha-aspartyl-L-valyl-L-valyl-;Tyr-Ala-Phe-Asp-Val-val-Gly-nh2;deltorphin I, Ala(2)- |
| CAS号 | 122752-15-2 |
| 分子式 | C37H52N8O10 |
| 分子量 | 768.86 |
| EINECS号 | |
| 相关类别 | 标准品;Peptide;Opioid receptor and opioid-like receptor |
| Mol文件 | 122752-15-2.mol |
| 结构式 |  |
DELTORPHIN I 性质
| 沸点 | 1242.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.284±0.06 g/cm3(Predicted) |
| 储存条件 | -15°C |
| 溶解度 | 在 50% 乙腈/水中可溶解至 0.40 mg/ml |
| 酸度系数(pKa) | 4.19±0.10(Predicted) |
| 形态 | 粉末 |
Deltorphin I 是一种高亲和力的选择性 δ-阿片受体 (δ-opioid receptor) 激动剂。
δ-opioid receptor
Twice daily administration of Deltorphin I (20μg/mouse) for 4 days produces tolerance to Deltorphin I analgesia, as shown by the decrease in the analgesic response. The peak analgesic response to Deltorphin I (20 μg/mouse) at 10 min after injections is decreased from 8.36±0.28 s (the 1st day) to 4.53±0.14 s (the 4th day) markedly. Concurrent treatment of Melatonin (0.5, 1 and 2.5 mg/kg) and Deltorphin I (20 μg/mouse) twice daily for 4 days can attenuate the tolerance to Deltorphin I analgesia (P<0.05, <0.05 and <0.05), and this effect is dose dependent.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-P1336 | DELTORPHIN I Deltorphin I | 122752-15-2 | 5 mg | 2000元 |
| 2024/04/30 | HY-P1336 | Deltorphin I | 10 mg | 3100元 |