- 2-Chlorobenzoyl Chloride
-
- $10.00 / 25Kg/Bag
-
2025-02-13
- CAS:609-65-4
- Min. Order: 25Kg/Bag
- Purity: 99.99%
- Supply Ability: 100ton
|
| 2-Chlorobenzoyl chloride Basic information |
| 2-Chlorobenzoyl chloride Chemical Properties |
Melting point | -4--3 °C (lit.) | Boiling point | 238 °C (lit.) | density | 1.382 g/mL at 25 °C (lit.) | vapor pressure | 0.1 hPa (20 °C) | refractive index | n20/D 1.572(lit.) | Fp | >230 °F | storage temp. | Store below +30°C. | form | Liquid | color | Clear colorless to very slightly yellow | explosive limit | 1.5-9.4%(V) | Water Solubility | Soluble in acetone, ether, and alcohol. Solubility in water it decomposes. | Sensitive | Moisture Sensitive | BRN | 386435 | CAS DataBase Reference | 609-65-4(CAS DataBase Reference) | NIST Chemistry Reference | Benzoyl chloride, 2-chloro-(609-65-4) | EPA Substance Registry System | Benzoyl chloride, 2-chloro- (609-65-4) |
Hazard Codes | C | Risk Statements | 34 | Safety Statements | 26-36/37/39-45-28A | RIDADR | UN 3265 8/PG 2 | WGK Germany | 1 | F | 19-21 | Autoignition Temperature | 600 °C | Hazard Note | Corrosive/Moisture Sensitive | TSCA | Yes | HazardClass | 8 | PackingGroup | II | HS Code | 29163900 | Toxicity | LD50 orally in Rabbit: 3250 mg/kg |
| 2-Chlorobenzoyl chloride Usage And Synthesis |
Chemical Properties | clear colourless to very slightly yellow liquid | Uses | 2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide. | Definition | ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the ortho-position. | General Description | 2-Chlorobenzoyl chloride reacts with aromatic amines and ammonium thiocyanate using polyethylene glycol-400 as the catalyst under the condition of solid-liquid phase-transfer catalysis to form N-aryl-N′(2-chlorobenzoyl) thioureas. 2-Chlorobenzoyl chloride causes the acylation of polystyrene during the preparation and regeneration of the polystyrene-based resin. | Synthesis | A process for preparing 2-chlorobenzoyl chloride which comprises reacting 2-chlorobenzaldehyde with chlorine in the presence of phosphorus pentachloride at a temperature of from 50° to 200° C. and wherein the 2-chlorobenzaldehyde: phosphorus pentachloride ratio is from 1:0.05 to 1:0.2.
Phosphorus pentachloride (41.5 g, 0.2 mole) was added to 2-chlorobenzaldehyde (289.7 g, 2.0 mole, 97%). After the ensuing exotherm had subsided, the resulting red solution was heated to 160° C. A stream of chlorine was introduced through a sparge tube into the solution for six hours. (Gas chromatography indicated 96.5% conversion.) The solution was then cooled and distilled under reduced pressure, giving 325.4 grams of 2-chlorobenzoyl chloride, which boiled at 135° to 140° C. at 16 millimeters of mercury. The yield of 2-Chlorobenzoyl chloride was 93% (98.5% pure). |
| 2-Chlorobenzoyl chloride Preparation Products And Raw materials |
|