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| | 3-Cyclohexylaminopropanesulfonic Acid Basic information |
| | 3-Cyclohexylaminopropanesulfonic Acid Chemical Properties |
| Melting point | >300 °C(lit.) | | density | 1.1809 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5250 (estimate) | | Fp | >110℃ | | storage temp. | room temp | | solubility | H2O: 0.5 M at 20 °C, clear | | form | Powder/Solid | | color | White | | PH | 3.0-7.0 (20℃, 0.5M in H2O) | | pka | 10.4(at 25℃) | | Odor | Odorless | | PH Range | 3 - 7 | | Water Solubility | 9 g/100 mL (20 ºC) | | λmax | λ: 260 nm Amax: ≤0.04
λ: 280 nm Amax: ≤0.04 | | Merck | 14,1767 | | BRN | 2835588 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | LogP | 0.3 at 25℃ | | CAS DataBase Reference | 1135-40-6(CAS DataBase Reference) | | EPA Substance Registry System | 1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6) |
| | 3-Cyclohexylaminopropanesulfonic Acid Usage And Synthesis |
| Chemical Properties | White/clear crystalline powder | | Description | 3-Cyclohexylaminopropanesulfonic Acid, also known as 3-(Cyclohexylamino)-1-propanesulfonic acid (CHAPS) or N-Cyclohexyl-3-aminopropanesulfonic acid, is a detergent with a high affinity for basic proteins that can be used to extract these proteins from biological samples and solubilize them. CHAPS is a type of ampholyte, which means it has both anionic and cationic groups. | | Uses | 3-Cyclohexylaminopropanesulfonic Acid buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good's buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects. It is a biological buffer.
| | Definition | ChEBI: Cyclohexylaminopropanesulfonic acid is an amine. | | Flammability and Explosibility | Not classified |
| | 3-Cyclohexylaminopropanesulfonic Acid Preparation Products And Raw materials |
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