- 4-Cyclohexylphenol
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- $0.00 / 1kg
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2023-10-16
- CAS:1131-60-8
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20tons
- 4-Cyclohexylphenol
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- $54.60 / 1KG
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2023-03-06
- CAS:1131-60-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000kg
- 4-Cyclohexylphenol
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- $100.00 / 10kg
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2022-10-25
- CAS:1131-60-8
- Min. Order: 1kg
- Purity: 99
- Supply Ability: 10000kg/week
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| | 4-Cyclohexylphenol Basic information |
| Product Name: | 4-Cyclohexylphenol | | Synonyms: | Phenol, p-cyclohexyl-;p-Hydroxyphenylcyclohexane;CYCLOHEXYL PHENOL;4-cyclohexyl-pheno;4-HYDROXYPHENYLCYCLOHEXANE;4-CYCLOHEXYLPHENOL;P-CYCLOHEXYLPHENOL;CYCLOHEXYLPHENOL, 4- | | CAS: | 1131-60-8 | | MF: | C12H16O | | MW: | 176.25 | | EINECS: | 214-465-4 | | Product Categories: | Aromatic Phenols | | Mol File: | 1131-60-8.mol |  |
| | 4-Cyclohexylphenol Chemical Properties |
| Melting point | 130-135°C | | Boiling point | 213-215°C | | density | 0.9452 (rough estimate) | | vapor pressure | 0.823-3.6Pa at 25℃ | | refractive index | 1.5415 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | form | Solid:flakes | | pka | 10.15±0.13(Predicted) | | color | White to Light yellow to Light orange | | Water Solubility | 66.66mg/L(25 ºC) | | Dielectric constant | 4.0（54℃） | | LogP | 4.22-4.33 | | CAS DataBase Reference | 1131-60-8(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 4-cyclohexyl-(1131-60-8) | | EPA Substance Registry System | Phenol, 4-cyclohexyl- (1131-60-8) |
| | 4-Cyclohexylphenol Usage And Synthesis |
| Uses | 4-Cyclohexylphenol is a derivative of Cyclohexylphenol (CHP), which is widely used in the preparation of dyes, resins, and biocides[2]. 4-Cyclohexylphenol labelled with 35s can be used for metabolic studies[3]. | | Synthesis | 4-Cyclohexylphenol is obtained by hydroalkylation of phenol using phenol as a raw material in the presence of a palladium catalyst and a molten salt (NaCl-AlCl3)[1]. The specific synthesis steps are as follows:
The hydroalkylation of phenol in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out. By using 1% Pd-Al2O3 (1 g) and the fused salt (1 : 1 mol ratio, 6 g), 4-cyclohexylphenol was obtained selectively from 1 (30 g) in a yield of 31.9% at 120°C for 4.5 h.
| | References | [1] T. KAMIYAMA; M. I; S Enomoto. Hydroalkylation of phenol to cyclohexylphenol in the presence of Pd-Al2O3 and NaCl-AlCl3 under hydrogen pressure.[J]. Chemical & pharmaceutical bulletin, 1986. DOI:10.1248/CPB.34.450.
[2] S. GUTIéRREZ-RUBIO . Synthesis of cyclohexylphenol via phenol hydroalkylation using Co2P/zeolite catalysts[J]. Catalysis Today, 2022. DOI:10.1016/j.cattod.2021.11.039.
[3] D.J. HEARSE; Gillian M P; A H Olavesen. The preparation and characterization of a series of 35S-labelled aryl sulphate esters for metabolic studies[J]. Biochemical pharmacology, 1969. DOI:10.1016/0006-2952(69)90022-7.
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| | 4-Cyclohexylphenol Preparation Products And Raw materials |
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