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| | 1,2,3,4-Tetrahydro-1-naphthol Basic information |
| Product Name: | 1,2,3,4-Tetrahydro-1-naphthol | | Synonyms: | 1,2,3,4-tetrahydro-1-naphthaleno;1,2,3,4-Tetrahydro-1-naphthalenol;1,2,3,4-tetrahydro-1-naphtho;1,2,3,4-tetrahydro-1-napthol;1,2,3,4-Tetrahydro-alpha-naphthol;(S)-Tetralin-1-ol;(S)-Tetralin-1β-ol;1-Tetralinol | | CAS: | 529-33-9 | | MF: | C10H12O | | MW: | 148.2 | | EINECS: | 208-459-0 | | Product Categories: | Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols | | Mol File: | 529-33-9.mol |  |
| | 1,2,3,4-Tetrahydro-1-naphthol Chemical Properties |
| Melting point | 28-32 °C | | Boiling point | 102-104 °C2 mm Hg(lit.) | | density | 1.09 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.564(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | 5.09g/l | | form | powder to lump to clear liquid | | pka | 14.33±0.20(Predicted) | | color | White or Colorless to Light yellow | | Specific Gravity | 1.090 | | BRN | 2046227 | | Cosmetics Ingredients Functions | PERFUMING | | InChI | 1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10-11H,3,5,7H2 | | InChIKey | JAAJQSRLGAYGKZ-UHFFFAOYSA-N | | SMILES | OC1CCCc2ccccc12 | | LogP | 1.980 | | CAS DataBase Reference | 529-33-9(CAS DataBase Reference) | | NIST Chemistry Reference | 1-Naphthalenol, 1,2,3,4-tetrahydro-(529-33-9) | | EPA Substance Registry System | 1-Naphthalenol, 1,2,3,4-tetrahydro- (529-33-9) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 22-24/25-37/39-26 | | WGK Germany | 3 | | RTECS | QL5075000 | | TSCA | TSCA listed | | HS Code | 29062900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 1,2,3,4-Tetrahydro-1-naphthol Usage And Synthesis |
| Chemical Properties | clear colourless to slightly brown viscous liquid | | Uses | 1,2,3,4-Tetrahydro-1-naphthol was used as chiral probe to examine the role of three aromatic residues in enzyme-substrate interactions at the sulfuryl acceptor binding site of aryl sulfotransferase IV enzyme. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c | | General Description | (R)-(-)-enantiomer of 1,2,3,4-Tetrahydro-1-naphthol is a substrate for aryl sulfotransferase (AST) IV enzyme and (S)-(+)-1,2,3,4-tetrahydro-1-naphthol is a competitive inhibitor of AST IV-catalyzed sulfation of 1-naphthalenemethanol. It is the major urinary metabolite of tetralin. |
| | 1,2,3,4-Tetrahydro-1-naphthol Preparation Products And Raw materials |
| Raw materials | 1,2,3,4-Tetrahydronaphthalene-->[1,1'-Binaphthalene]-1,1'(2H,2'H)-diol, 3,3',4,4'-tetrahydro--->1,2,3,4-tetrahydro-1-naphthyl hydroperoxide-->1,2,3,4-TETRAHYDRO-2-NAPHTHOL-->1,2-DIHYDRONAPHTHALENE | | Preparation Products | Brodifacoum-->Flocoumafen-->Coumatetralyl-->5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid-->8-BROMO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE-->(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL-->5,6,7,8-TETRAHYDRO-1-NAPHTHOL-->2,3,4,5-Tetrahydro-1H-benzo[b]azepine-->1,2,3,4-Tetrahydro-1-naphthylamine-->2,3-Dihydro-1,4-naphthoquinone-->(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol |
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