| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:PDD 00017272
CAS:1945950-20-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:PDD00017272
CAS:1945950-20-8
Purity:98%+ HPLC Package:10mg，500mg，1g，2g，5g，10g，More
|
PDD 00017272 manufacturers
- PDD00017272
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- $99.00 / 1mg
-
2025-09-17
- CAS:1945950-20-8
- Min. Order:
- Purity: 98.18%
- Supply Ability: 10g
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| | PDD 00017272 Basic information |
| Product Name: | PDD 00017272 | | Synonyms: | PDD 00017272;6-Quinazolinesulfonamide, 1-[(2,4-dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo- | | CAS: | 1945950-20-8 | | MF: | C23H25N5O4S3 | | MW: | 531.67 | | EINECS: | | | Product Categories: | | | Mol File: | 1945950-20-8.mol |  |
| | PDD 00017272 Chemical Properties |
| Boiling point | 733.6±70.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 11.63±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | PDD 00017272 Usage And Synthesis |
| Uses | PDD00017272 (34f) is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 of 4.8 nM and 9.2 nM in biochemical assay and cell POM, respectively[1]. | | storage | Store at -20°C | | References | [1] Bohdan Waszkowycz, et al. Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J Med Chem. 2018 Dec 13;61(23):10767-10792. DOI:10.1021/acs.jmedchem.8b01407 |
| | PDD 00017272 Preparation Products And Raw materials |
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