| | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate Basic information |
| Product Name: | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate | | Synonyms: | O,O-diethyl S-(2-diethylaminoethyl)phosphorothioate;O,O-DIETHYL-5-[2-(DIETHYLAMINO)ETHYL]PHOSPHONOTHIOATE;Amiton: (O,O-Diethyl-S-(2-diethylaminoethyl) thiophosphate);DSDP;Inferno;Metramac;Phosphorothioic acid S-(2-diethylaminoethyl) O,O-diethyl;R-5158 | | CAS: | 78-53-5 | | MF: | C10H24NO3PS | | MW: | 269.34 | | EINECS: | | | Product Categories: | | | Mol File: | 78-53-5.mol | ![S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate Structure](CAS/GIF/78-53-5.gif) |
| | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate Chemical Properties |
| | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate Usage And Synthesis |
| Chemical Properties | Amiton is a liquid organophosphate. | | Uses | Insecticide. | | General Description | Liquid. Used as an acaricide and insecticide. | | Reactivity Profile | Organothiophosphates, such as S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | | Hazard | Cholinesterase inhibitor. Use may be
restricted. | | Health Hazard | One of the most toxic organophosphorusinsecticides; highly toxic by oral route;effects are cumulative; toxic symptoms aresimilar to those of other cholinesteraseinhibitors and include nausea, vomiting, diar-rhea, excessive salivation, blurred vision andpain in eye muscle, convulsion, coma, andrespiratory failure; probable lethal dose isestimated to be 5–10 g for adult humans. | | Health Hazard | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate is highly toxic orally. It is a cholinesterase inhibitor. | | Fire Hazard | When heated to decomposition, can emit toxic fumes of oxides of nitrogen, phosphorus, and sulfur. (Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire may produce irritating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. Avoid extreme heat. | | Potential Exposure | Amiton is used as an acaricide and an
insecticide; exposure may occur in manufacture and in
application and use. VG has been used as a military nerve
agent. | | Shipping | UN3018 Organophosphorus pesticides, liquid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous material. | | Purification Methods | Recrystallise it from isopropanol/diethyl ether. [Ailman & Magee in Organo Phosphorus Compound (Kosolapoff & Maier eds) Wiley Vol 7 pp 487-871 1976.] Diethylmethylsilane [760 -32 -7] M 102.3, b 78.4o/760mm, 77.2 -77.6o/atm, d 4 0.71. Fractionally distil it through a ca 20-plate column, and the fraction boiling within a range of less than 0.5o is collected. It is a flammable irritating liquid. [Price J Am Chem Soc 69 2600 1947, Beilstein 4 III 1847.] | | Incompatibilities | Contact with strong oxidizers may cause
release of toxic phosphorus oxides. Incompatible with oxidizers
(chlorates, nitrates, peroxides, permanganates, perchlorates,
chlorine, bromine, fluorine, etc.); contact may
cause fires or explosions. Keep away from alkaline materials,
strong bases, strong acids, oxoacids, epoxides.
Organophosphates, in the presence of strong reducing
agents such as hydrides, may form highly toxic and flammable
phosphine gas. Keep away from alkaline materials. | | Waste Disposal | Use a licensed professional
waste disposal service to dispose of this material. All federal,
state, and local environmental regulations must be
observed. High-temperature incineration. Hydrolysis may
also be used. In accordance with 40CFR165, follow
recommendations for the disposal of pesticides and pesticide
containers. Must be disposed properly by following
package label directions or by contacting your local or federal
environmental control agency, or by contacting your
regional EPA office. |
| | S-[2-(Diethylamino)ethyl]O，O-diethylphosphorothioate Preparation Products And Raw materials |
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