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2-Chloropyridine

2-Chloropyridine Basic information
Product Name:2-Chloropyridine
Synonyms:2-Chloropyridine ,99%;2-Pyridinyl chloride;2-Chloro Pyridine (2CP);NSC 4649;2- chlorinepyridine;2-Chloropyridi;2-chloro-pyridin;o-Chloropyridine
CAS:109-09-1
MF:C5H4ClN
MW:113.54
EINECS:203-646-3
Product Categories:Amines;Aromatics;Bases & Related Reagents;Mutagenesis Research Chemicals;Nucleotides;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines;Chloropyridines;Halopyridines;API Intermediate;Pharmaceutical Intermediates;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines derivates
Mol File:109-09-1.mol
2-Chloropyridine Structure
2-Chloropyridine Chemical Properties
Melting point -46 °C
Boiling point 166 °C/714 mmHg (lit.)
density 1.2 g/mL at 25 °C (lit.)
vapor pressure 1.7 mm Hg ( 20 °C)
refractive index n20/D 1.532(lit.)
Fp 149 °F
storage temp. Refrigerator
solubility 27g/l
form Liquid
pka0.49(at 25℃)
color Clear colorless to light yellow
PH6-7 (27g/l, H2O, 20℃)
Water Solubility 27 g/L (20 ºC)
BRN 105788
CAS DataBase Reference109-09-1(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 2-chloro-(109-09-1)
EPA Substance Registry System2-Chloropyridine (109-09-1)
Safety Information
Hazard Codes T
Risk Statements 23/24/25-36/37/38
Safety Statements 26-36/37/39-45-28A-27
RIDADR UN 2822 6.1/PG 2
WGK Germany 3
RTECS US5950000
Hazard Note Toxic
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 29333999
Hazardous Substances Data109-09-1(Hazardous Substances Data)
MSDS Information
ProviderLanguage
2-Chloropyridine English
SigmaAldrich English
ACROS English
ALFA English
2-Chloropyridine Usage And Synthesis
Chemical PropertiesClear colourless to light yellow liquid
Uses2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products.
Uses2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during t he decomposition of specific insecticides.
DefinitionChEBI: 2-chloropyridine is a monochloropyridine.
Synthesis Reference(s)Synthetic Communications, 19, p. 897, 1989 DOI: 10.1080/00397918908051009
Synthesis, p. 337, 1990
General DescriptionA colorless oily liquid. Toxic by ingestion and/or skin absorption. Used to make other chemicals.
Air & Water ReactionsSlightly soluble in water and denser than water.
HazardToxic by ingestion.
Fire HazardCombustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Safety ProfilePoison by ingestion, inhalation, skin contact, and intraperitoneal routes. Combustible when exposed to heat or flame. Can react with oxidizing materials. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and phosgene.
Purification MethodsDry 2-chloropyridine with NaOH for several days, then distil it from CaO under reduced pressure. [Beilstein 20/5 V 402.]
Tag:2-Chloropyridine(109-09-1) Related Product Information
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