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betazole

betazole Suppliers list
Company Name: Accela ChemBio Inc.
Tel: (+1)-858-699-3322
Email: info@accelachem.com
Products Intro: Product Name:2-(3-Pyrazolyl)ethanamine
CAS:105-20-4
Purity:95% Package:0.25g;1g Remarks:SY021017
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:betazole
CAS:105-20-4
Purity:Min98% HPLC/GC Package:1KG;8USD
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-89586680 +86-18192503167
Email: 1026@dideu.com
Products Intro: Product Name:betazole USP/EP/BP
CAS:105-20-4
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:betazole
CAS:105-20-4
Purity:0.999 Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Nanjing Hengbei Chemicals Co., Ltd.
Tel: +86-25-58393656
Email: sales@hengbeichem.cn
Products Intro: Product Name:2-(3-Pyrazolyl)ethanamine
CAS:105-20-4
Package:1g;10g;1Kg

betazole manufacturers

  • betazole USP/EP/BP
  • betazole USP/EP/BP pictures
  • $1.10 / 1g
  • 2021-08-13
  • CAS:105-20-4
  • Min. Order: 1g
  • Purity: 0.999
  • Supply Ability: 100 Tons min
betazole Basic information
Product Name:betazole
Synonyms:3-(2-Aminoethyl)-1H-pyrazole;2-(1H-pyrazol-5-yl)ethanamine(SALTDATA: FREE);2-(1H-pyrazol-5-yl)ethanamine;2-(3-Pyrazolyl)ethanamine;betazole;Ametazole;1H-Pyrazole-3-ethanamine;betazole USP/EP/BP
CAS:105-20-4
MF:C5H9N3
MW:111.15
EINECS:203-278-3
Product Categories:
Mol File:105-20-4.mol
betazole Structure
betazole Chemical Properties
Melting point 25°C
Boiling point bp0.5 118-123°
density 0.9902 (rough estimate)
refractive index 1.4690 (estimate)
storage temp. 4°C, protect from light
solubility DMSO: 250 mg/mL (2249.21 mM)
pka14.39±0.10(Predicted)
Safety Information
MSDS Information
betazole Usage And Synthesis
OriginatorHistalog,Lilly,US,1953
DefinitionChEBI: Pyrazole in which a hydrogen adjacent to one of the nitrogen atoms is substituted by a 2-aminoethyl group. It is a histamine H2-receptor agonist used clinically to test gastric secretory function.
Manufacturing ProcessA solution of 55 grams (1.1 mol) of hydrazine hydrate in 100 ml of methanol was cooled in a water bath and stirred while a solution of 48 grams (0.50 mol) of pure γ-pyrone in 100 ml of methanol was added over a period of about 15 minutes. After the addition was complete, the solution was allowed to stand at room temperature for about 1 hour, and was placed in a 1 liter hydrogenation bomb. 25 ml of liquid ammonia were added cautiously with stirring, followed by about 15 cc of Raney nickel catalyst. The bomb was charged with hydrogen to 1,800 pounds pressure, heated to 90°C and agitated. The quantity of hydrogen required to convert the hydrazone into the desired aminoethylpyrazole was taken up in about 3 hours. The bomb was cooled and opened, and the contents filtered. The filtrate was evaporated under reduced pressure to remove the methanol and the residual liquid was distilled under reduced pressure, whereby there were obtained 44.5 grams (81% yield) of 3-β-aminoethylpyrazole boiling at 118°-123°C at a pressure of 0.5 mm of Hg.
Brand nameHistalog (Lilly).
Therapeutic FunctionDiagnostic aid (gastric secretion)
betazole Preparation Products And Raw materials
Raw materialsHydrogen-->Hydrazine hydrate
Tag:betazole(105-20-4) Related Product Information
2-(4-FLUOROPHENYL)-5-(4-NITROPHENYL)-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE 1-BENZYL-5-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRAZOL-5-YL)-3-(4-FLUOROBENZYL)-2,4(1H,3H)-PYRIMIDINEDIONE 5-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE 2-(6-CHLORO-2-PYRIDINYL)-5-(4-NITROPHENYL)-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE 11-(3-CHLOROPHENYL)-5,11,12,12A-TETRAHYDROPYRAZOLO[3',4':4,5]PYRIDO[2,1-A]ISOQUINOLIN-8(6H)-ONE 1-(4-CHLOROPHENYL)-5-(1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRAZOL-5-YL)-3-(4-FLUOROBENZYL)-2,4(1H,3H)-PYRIMIDINEDIONE 6-(1H-PYRAZOL-5-YL)-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-5-ONE 11-PHENYL-5,11,12,12A-TETRAHYDROPYRAZOLO[3',4':4,5]PYRIDO[2,1-A]ISOQUINOLIN-8(6H)-ONE 2-(2,4-DIFLUOROPHENYL)-4-METHYL-6-(1H-PYRAZOL-5-YL)-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE 3-(1H-PYRAZOL-5-YL)-4H-PYRIMIDO[2,1-B][1,3]BENZOTHIAZOL-4-ONE 11-(4-CHLOROPHENYL)-5,11,12,12A-TETRAHYDROPYRAZOLO[3',4':4,5]PYRIDO[2,1-A]ISOQUINOLIN-8(6H)-ONE 11-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-5,11,12,12A-TETRAHYDROPYRAZOLO[3',4':4,5]PYRIDO[2,1-A]ISOQUINOLIN-8(6H)-ONE 6-(1H-PYRAZOL-5-YL)-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-5-ONE 2-(4-CHLOROPHENYL)-6-[1-(1,1-DIOXOTETRAHYDRO-1H-1LAMBDA6-THIOPHEN-3-YL)-1H-PYRAZOL-5-YL]-4-METHYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE 5-(4-NITROPHENYL)-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE 5-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(4-METHYLPHENYL)-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE 4-METHYL-6-[1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE 5-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-PHENYL-4,5,6,7-TETRAHYDRO-2H-PYRAZOLO[4,3-C]PYRIDINE