(R)-Hydroxychloroquine sulfate

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CAS:2488706-20-1
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Products Intro: Product Name:(R)-Hydroxychloroquine Sulfate
CAS:2488706-20-1
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Products Intro: Product Name:(R)-Hydroxychloroquine (sulfate)
CAS:2488706-20-1
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CAS:2488706-20-1
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Products Intro: Product Name:(R)-Hydroxychloroquine (sulfate)
(R)-Hydroxychloroquine sulfate Basic information
Product Name:(R)-Hydroxychloroquine sulfate
Synonyms:(R)-Hydroxychloroquine sulfate;2-[[(4R)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol, monosulfate
CAS:2488706-20-1
MF:C18H28ClN3O5S
MW:433.95
EINECS:
Product Categories:
Mol File:2488706-20-1.mol
(R)-Hydroxychloroquine sulfate Structure
(R)-Hydroxychloroquine sulfate Chemical Properties
storage temp. -20°C
solubility DMSO: soluble,Methanol: soluble
form A solid
Water Solubility Water: soluble
Safety Information
MSDS Information
(R)-Hydroxychloroquine sulfate Usage And Synthesis
Uses(R)-Hydroxychloroquine ((R)-HCQ) phosphate is a (R)-isomer of Hydroxychloroquine (HY-W031727). (R)-Hydroxychloroquine inhibits the insulin metabolizing enzyme of cytosolic fraction of liver homogenates in healthy and diabetic rats[1].
Biological Activity(R)-Hydroxychloroquine is an isomer of hydroxychloroquine .1 (R)-Hydroxychloroquine (2.5-20 mg/ml) reduces the rate of insulin degradation in isolated liver homogenates from non-diabetic and diabetic rats. Formulations containing hydroxychloroquine have been used in the prevention or treatment of malaria, as well as in the treatment of rheumatoid arthritis and systemic lupus erythematosus.
References1.Emami, J., Pasutto, F.M., Mercer, J.R., et al.Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic ratsLife Sci.64(5)325-335(1999)
(R)-Hydroxychloroquine sulfate Preparation Products And Raw materials
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