(+)-Dihydrexidine hydrochloride NEW
| Price | $1970 | $2580 | $3400 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: (+)-Dihydrexidine hydrochloride | CAS No.: 158704-02-0 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | (+)-Dihydrexidine hydrochloride |
| Description | (+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM). |
| In vitro | (+)-Dihydrexidine hydrochloride (DHX) is a high-potency, bioavailable agonist of D1 dopamine receptors. It is inactive (IC50 > 10 μM) against 40 other binding sites except D2 dopamine receptors (IC50 = 130 nM) and alpha-2 adrenoreceptors (IC50 = 230 nM). DHX competes stereoselectively and potently for D1 binding sites in rat striatal membranes labeled with [3H]SCH23390 with an IC50 of approximately 10 nM, compared to around 30 nM for the prototypical D1 agonist SKF38393. |
| In vivo | To assess the functional status of striatal neurons in response to D1 receptor activation, AC5+/+ and AC5-/- mice were injected with the D1 agonist (+)-Dihydrexidine (30 mg/kg, i.p.). After 45 minutes, the dorsal-lateral striatum and NAc were separately collected for RT-PCR analysis. The results indicate that (+)-Dihydrexidine significantly enhances the induction of immediate early genes c-fos, egr-1, and junB in the NAc of AC5-/- mice compared to AC5+/+ mice, while the induction in the dorsal-lateral striatum is suppressed in AC5-/- mice [3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Dopamine D1 receptor | Dihydrexidine Hydrochloride | DAR-0100 | DAR0100 | DAR 0100 | (+)Dihydrexidine hydrochloride | (+) Dihydrexidine hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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